{"id":"W1985501043","doi":"10.1210/mend.15.8.0685","title":"Members of the Kv1 and Kv2 Voltage-Dependent K+ Channel Families Regulate Insulin Secretion","year":2001,"lang":"en","type":"article","venue":"Molecular Endocrinology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":185,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Biology; Internal medicine; Endocrinology; Tolbutamide; Secretion; Potassium channel; Insulin; Pancreatic islets; Islet; Cell biology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008200233,0.0001513644,0.0001463241,0.00007531927,0.0000862119,0.000009124295,0.0001395124,0.0001467617,0.0000286406],"category_scores_gemma":[0.00006633624,0.0001251022,0.00008974929,0.000122609,0.0001901279,0.00000453014,0.0001726471,0.00009672274,0.000004194142],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001289231,"about_ca_system_score_gemma":0.00002570069,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005299323,"about_ca_topic_score_gemma":0.00003649898,"domain_scores_codex":[0.9989796,0.0000965587,0.0002191886,0.0003143701,0.0001410619,0.0002492309],"domain_scores_gemma":[0.999395,0.00000685785,0.0001122253,0.0003463789,0.00009249908,0.00004708428],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000199855,0.00005534392,0.001925692,0.00002241066,0.00008734848,0.00001740177,0.0001171596,0.002133779,0.9870573,0.001939898,0.0003600352,0.006083764],"study_design_scores_gemma":[0.001934282,0.0003729835,0.01593139,0.00002037771,0.00005737408,0.0004734144,0.000418947,0.001962462,0.9213666,0.001263946,0.05584924,0.0003490358],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9878831,0.0008391773,0.008179634,0.0006218957,0.0005499182,0.0002147145,0.000006643676,0.00001939705,0.001685551],"genre_scores_gemma":[0.9974847,0.0007044309,0.00004922222,0.0003649204,0.0001039588,0.00001914117,0.00004407634,0.00001993986,0.001209652],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06569076,"threshold_uncertainty_score":0.5101519,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00867075053149078,"score_gpt":0.222301163709362,"score_spread":0.2136304131778712,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}