{"id":"W1985505412","doi":"10.1210/mend.15.9.0692","title":"Modulation of Endogenous GATA-4 Activity Reveals Its Dual Contribution to Mullerian Inhibiting Substance Gene Transcription in Sertoli Cells","year":2001,"lang":"en","type":"article","venue":"Molecular Endocrinology","topic":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre hospitalier de l'Université Laval","funders":"","keywords":"Biology; Zinc finger; GATA transcription factor; Transcription factor; Transactivation; Cell biology; Zinc finger transcription factor; GATA1; GATA2; Gene; Molecular biology; Promoter; Gene expression; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001938622,0.000300171,0.0003147607,0.0001293255,0.0001045632,0.0003088214,0.0002426029,0.0002178149,0.0007167264],"category_scores_gemma":[0.0001948787,0.0001996937,0.0001935687,0.00008040028,0.0002361396,0.0001739824,0.00014994,0.0004166434,0.0002514684],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004129981,"about_ca_system_score_gemma":0.0002818104,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006550455,"about_ca_topic_score_gemma":0.001114839,"domain_scores_codex":[0.9998049,0.00003556896,0.00001540379,0.0000459433,0.00005308069,0.0000451301],"domain_scores_gemma":[0.9998236,0.00005144285,0.00003721466,0.00001902563,0.00001784683,0.00005089383],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005421069,0.000003352149,0.000106786,0.000007711623,0.000001199552,0.000008616641,0.000002740708,0.00002164031,0.9996153,0.00004834938,0.000001954139,0.0001280565],"study_design_scores_gemma":[0.000009124648,0.0001091513,0.00188142,0.00000220311,0.00001045364,0.00008024519,0.000008889795,0.00102365,0.9961956,0.00001984842,0.0006562771,0.00000319062],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963558,0.0007940326,0.002198649,0.00003341022,0.00001236162,0.000008528878,0.0001073227,0.0000208566,0.0004690083],"genre_scores_gemma":[0.9952135,0.0004506434,0.002839446,0.0000352176,0.00001059256,0.00001525479,0.0003095429,0.0000266348,0.001099247],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007167264,"threshold_uncertainty_score":0.002996564,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02180800230608763,"score_gpt":0.2576698513766592,"score_spread":0.2358618490705716,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}