{"id":"W1985505412","doi":"10.1210/mend.15.9.0692","title":"Modulation of Endogenous GATA-4 Activity Reveals Its Dual Contribution to Mullerian Inhibiting Substance Gene Transcription in Sertoli Cells","year":2001,"lang":"en","type":"article","venue":"Molecular Endocrinology","topic":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre hospitalier de l'Université Laval","funders":"","keywords":"Biology; Zinc finger; GATA transcription factor; Transcription factor; Transactivation; Cell biology; Zinc finger transcription factor; GATA1; GATA2; Gene; Molecular biology; Promoter; Gene expression; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001185981,0.0001764971,0.0002778641,0.00009446107,0.0000501664,0.00001026901,0.0001200298,0.000153968,0.00003350664],"category_scores_gemma":[0.00006812222,0.0001955592,0.00009640852,0.0001587269,0.00005863353,0.000009671222,0.00004385513,0.000103302,0.00001142351],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002736195,"about_ca_system_score_gemma":0.00002940134,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003315408,"about_ca_topic_score_gemma":0.00008727933,"domain_scores_codex":[0.9984904,0.00015436,0.0004186044,0.0003900353,0.0001445084,0.0004020813],"domain_scores_gemma":[0.9993932,0.0000152414,0.0001331747,0.0002131278,0.0001572831,0.00008792539],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002162362,0.0001303311,0.0008222939,0.00001778329,0.00002016069,0.0001021498,0.00007329117,0.0008211973,0.9948623,0.000409443,0.000005462789,0.00251941],"study_design_scores_gemma":[0.00104938,0.0004212714,0.009131107,0.00001842366,0.00001236273,0.0001266084,0.00006002741,0.0001248178,0.9880016,0.0001635252,0.0006978579,0.0001930435],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943094,0.0003451376,0.004171222,0.0002422221,0.0001271254,0.0003471629,0.00003109828,0.00001490248,0.0004117228],"genre_scores_gemma":[0.9987917,0.0003053939,0.0002891244,0.0002607389,0.00006705533,0.00003948484,0.00008500327,0.000016775,0.0001447175],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008308814,"threshold_uncertainty_score":0.7974672,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02180800230608763,"score_gpt":0.2576698513766592,"score_spread":0.2358618490705716,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}