{"id":"W1985530751","doi":"10.4161/cc.19824","title":"Discordance between phosphorylation and recruitment of 53BP1 in response to DNA double-strand breaks","year":2012,"lang":"en","type":"article","venue":"Cell Cycle","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Ontario Institute for Cancer Research; University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research","keywords":"Chromatin; DNA damage; Biology; Phosphorylation; Molecular biology; DNA repair; Cell biology; DNA; DNA replication; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003270105,0.00008045506,0.0001019139,0.00003031359,0.00001709574,0.000006388166,0.00006452846,0.00006753392,0.000006314143],"category_scores_gemma":[0.00001379935,0.00008076718,0.00002406579,0.00005807416,0.0000206774,0.000006420802,0.0000621111,0.00003441445,0.000005218333],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001441927,"about_ca_system_score_gemma":0.0000162596,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002405816,"about_ca_topic_score_gemma":0.00001328233,"domain_scores_codex":[0.9994045,0.00004600905,0.0001434113,0.0001657715,0.00006945918,0.0001708798],"domain_scores_gemma":[0.9996426,0.00001515663,0.00004346754,0.0001980386,0.00001359697,0.00008720883],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006438424,0.00004843524,0.01634058,0.0000133168,0.000005120637,4.22955e-7,0.0002166582,0.00001577344,0.9805341,0.00002023016,0.00002951329,0.00213206],"study_design_scores_gemma":[0.0007296714,0.000160685,0.0821179,0.00001149212,0.00000694198,9.227674e-7,0.0000652541,0.000004740597,0.9142168,0.00003575656,0.002560467,0.00008943267],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980834,0.0004094174,0.0004340438,0.00004790078,0.00005884577,0.0003283124,0.00001000978,0.000004912271,0.0006231445],"genre_scores_gemma":[0.9985662,0.00002220686,0.0009152427,0.00002844474,0.0000528528,0.00003135385,0.00001843907,0.00001192763,0.0003533544],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06631732,"threshold_uncertainty_score":0.329359,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02325565135364808,"score_gpt":0.2774831447665397,"score_spread":0.2542274934128916,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}