{"id":"W1985583953","doi":"10.1186/1471-2350-15-22","title":"Evidence for synergistic effects of PRNP and ATP7Bmutations in severe neuropsychiatric deterioration","year":2014,"lang":"en","type":"article","venue":"BMC Medical Genetics","topic":"Trace Elements in Health","field":"Nursing","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Agency of Canada; McMaster University","funders":"","keywords":"PRNP; Genotype; Allele; Human genetics; Disease; Biology; Genetics; Asymptomatic; Compound heterozygosity; Gene; Medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006709369,0.0005966111,0.0004858121,0.0009726116,0.0003602138,0.0003287811,0.0005145189,0.0008853632,0.004855618],"category_scores_gemma":[0.001023518,0.0003022907,0.0004998823,0.0003610501,0.0007451454,0.0002701119,0.0009546102,0.000433522,0.0004866316],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001768373,"about_ca_system_score_gemma":0.0001840764,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002950536,"about_ca_topic_score_gemma":0.0003024075,"domain_scores_codex":[0.999338,0.0001736921,0.0001046841,0.0001672676,0.0001427123,0.00007359412],"domain_scores_gemma":[0.9983871,0.0006072951,0.0004633458,0.0001688839,0.0001341198,0.0002393236],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00970713,0.000668661,0.3506557,0.001000826,0.0009343927,0.1053576,0.0005240653,0.0005405102,0.5014643,0.0009500594,0.001716848,0.0264799],"study_design_scores_gemma":[0.000452712,0.003066525,0.556209,0.000116192,0.001275504,0.3448374,0.0003146094,0.00143934,0.08481497,0.001634608,0.00577141,0.00006772261],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947265,0.002132086,0.0007604451,0.0002144017,0.00003056753,0.00001949348,0.0001864406,0.00005428137,0.001875808],"genre_scores_gemma":[0.9987571,0.000333735,0.0004813159,0.00006996065,0.00003813524,0.000008335425,0.0001312199,0.000005752488,0.0001744303],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004855618,"threshold_uncertainty_score":0.01624364,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04382075218743636,"score_gpt":0.3578799948213908,"score_spread":0.3140592426339544,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}