{"id":"W1985634736","doi":"10.1021/jo801411p","title":"Povarov Reactions Involving 3-Aminocoumarins: Synthesis of 1,2,3,4-Tetrahydropyrido[2,3-<i>c</i>]coumarins and Pyrido[2,3-<i>c</i>]coumarins","year":2008,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Tautomer; Diastereomer; Chemistry; Cycloaddition; Condensation; Medicinal chemistry; Stereochemistry; Organic chemistry; Catalysis; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001537762,0.0003643144,0.0002276772,0.0002808309,0.000277895,0.0002865214,0.000237728,0.0003868289,0.0008294802],"category_scores_gemma":[0.0002547906,0.0001762907,0.0002678319,0.0002809418,0.0001877035,0.0004492975,0.0002911876,0.0005279445,0.0003891811],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002548117,"about_ca_system_score_gemma":0.0001780438,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003197835,"about_ca_topic_score_gemma":0.0005921106,"domain_scores_codex":[0.9998487,0.00003714255,0.000009496789,0.00003744379,0.00002814836,0.00003898402],"domain_scores_gemma":[0.9999162,0.00001738537,0.00002322728,0.0000146258,0.00001113642,0.00001748001],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006707032,0.00003085215,0.0001310826,0.0001018383,0.0000140166,0.000203713,0.00008448973,0.0005385434,0.9900024,0.001623264,0.00006971955,0.007133106],"study_design_scores_gemma":[0.00000682555,0.0001434453,0.000475019,0.000003111428,0.000007051766,0.0002218854,0.00001143169,0.0003317067,0.9945028,0.0001894433,0.004101768,0.00000551715],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9421197,0.004570375,0.03965124,0.0001760376,0.00009912348,0.0001687341,0.0003005544,0.000181013,0.01273323],"genre_scores_gemma":[0.9806657,0.002027199,0.01112881,0.00005401946,0.00001357264,0.00006210229,0.0002139251,0.00002952005,0.005805103],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008294802,"threshold_uncertainty_score":0.002774894,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02434862651169116,"score_gpt":0.2242580305217309,"score_spread":0.1999094040100398,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}