{"id":"W1985635340","doi":"10.1021/ja902558j","title":"Hydrazides as Tunable Reagents for Alkene Hydroamination and Aminocarbonylation","year":2009,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Synthesis and Catalytic Reactions","field":"Chemistry","cited_by":89,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; AstraZeneca Canada","keywords":"Hydroamination; Chemistry; Reagent; Alkene; Intramolecular force; Hydrazide; Stereospecificity; Medicinal chemistry; Combinatorial chemistry; Organic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002262811,0.0004657003,0.000278474,0.0001874929,0.0001424813,0.000269044,0.0004104743,0.0003041287,0.001677273],"category_scores_gemma":[0.0002213402,0.0002978499,0.0001802865,0.0001575241,0.0003691656,0.0003468235,0.0004040743,0.000573509,0.0007406598],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002309502,"about_ca_system_score_gemma":0.0001724365,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002245298,"about_ca_topic_score_gemma":0.000528525,"domain_scores_codex":[0.9998803,0.00002472709,0.000007892684,0.0000243615,0.00003449231,0.00002824711],"domain_scores_gemma":[0.9999152,0.00002029545,0.00002902239,0.000009038301,0.000009133362,0.00001730263],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002155524,0.00002804316,0.0001727201,0.0002318051,0.00001753615,0.0001283734,0.00004539464,0.0004352485,0.9895324,0.001328818,0.0001779718,0.00768619],"study_design_scores_gemma":[0.00006063112,0.0003440723,0.0003956885,0.000008184568,0.0000176341,0.0002043814,0.00001319411,0.0007424929,0.9943442,0.0001250173,0.003732893,0.00001156958],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9548505,0.008127133,0.0238037,0.0002109789,0.0001193357,0.0002291229,0.0003532599,0.0004988517,0.01180713],"genre_scores_gemma":[0.9859931,0.003418549,0.007836253,0.0000593681,0.0000316491,0.00006074132,0.0001189711,0.00004525722,0.002436134],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001677273,"threshold_uncertainty_score":0.005611062,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009503091094615624,"score_gpt":0.2558805928185823,"score_spread":0.2463775017239667,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}