{"id":"W1985667612","doi":"10.4061/2009/949271","title":"Trial Designs Likely to Meet Valid Long-Term Alzheimer's Disease Progression Effects: Learning from the Past, Preparing for the Future","year":2009,"lang":"en","type":"article","venue":"International Journal of Alzheimer s Disease","topic":"Health Systems, Economic Evaluations, Quality of Life","field":"Economics, Econometrics and Finance","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Baycrest Hospital; McGill University; Montreal Neurological Institute and Hospital; University of Toronto; NeuroRx Research (Canada)","funders":"","keywords":"Term (time); Psychology; Disease; Alzheimer's disease; Gerontology; Cognitive psychology; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005373235,0.0002699884,0.0005785458,0.0002108411,0.0003689977,0.0004080212,0.001114622,0.00007792373,0.00008681585],"category_scores_gemma":[0.002602463,0.0002038063,0.0005237442,0.000116548,0.0000548127,0.0006228818,0.00009166273,0.0002629219,0.00007921438],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001795655,"about_ca_system_score_gemma":0.0003104755,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002211912,"about_ca_topic_score_gemma":0.0000101265,"domain_scores_codex":[0.9957666,0.0004588772,0.002576807,0.0004272091,0.000424086,0.0003464299],"domain_scores_gemma":[0.9937744,0.002219264,0.002634695,0.0004233145,0.0003385225,0.0006097854],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.07967397,0.002921629,0.5009225,0.000139384,0.01380844,0.0001778515,0.006709925,0.02024664,0.0000269813,0.03137669,0.2704827,0.07351335],"study_design_scores_gemma":[0.02333431,0.001158508,0.8987784,0.001015209,0.001900287,0.00001411681,0.0003493336,0.006082498,0.00004084513,0.01904132,0.04740697,0.0008782456],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4385502,0.1402956,0.03919531,0.3600966,0.01393658,0.006976038,0.0006332466,0.0001050959,0.0002113636],"genre_scores_gemma":[0.9768332,0.0002128043,0.001115287,0.01137509,0.0101559,0.0001951276,0.00005013308,0.00004068234,0.00002180073],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.538283,"threshold_uncertainty_score":0.8310981,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.226927011124091,"score_gpt":0.4459162730624959,"score_spread":0.2189892619384049,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}