{"id":"W1985698425","doi":"10.1634/stemcells.2007-0724","title":"Hypoxia Enhances Tumor Stemness by Increasing the Invasive and Tumorigenic Side Population Fraction","year":2008,"lang":"en","type":"article","venue":"Stem Cells","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":306,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"National Cancer Institute; Institute of Medical Science, University of Tokyo; Hospital for Sick Children; University of Toronto","keywords":"Biology; Side population; Population; Stromal cell; Stem cell; Hypoxia (environmental); Cancer research; Bone marrow; Hox gene; Cell biology; Pathology; Cancer stem cell; Immunology; Chemistry; Genetics; Gene expression; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005949998,0.0001583951,0.000138755,0.0001655383,0.00007488713,0.0001342383,0.00005589399,0.00008791508,0.001464817],"category_scores_gemma":[0.00004812903,0.00007127743,0.0001405479,0.0000601772,0.00008245595,0.00009913977,0.0001497907,0.000202931,0.0001990387],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007731815,"about_ca_system_score_gemma":0.00008172145,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003123358,"about_ca_topic_score_gemma":0.0006191369,"domain_scores_codex":[0.9999533,0.00000769765,0.00000359625,0.000009001293,0.00001679589,0.000009606055],"domain_scores_gemma":[0.9999263,0.00001906861,0.00001602507,0.000006017417,0.000009249317,0.00002329415],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002915495,0.000008751751,0.0004652646,0.00001023907,0.000001669624,0.00001984825,0.000008490048,0.0000159606,0.9982675,0.00002224523,0.00001730323,0.001133583],"study_design_scores_gemma":[0.000007268477,0.0005116854,0.03169122,0.000004826092,0.0000131143,0.000498588,0.00003952347,0.0008744652,0.9641083,0.00004170424,0.00220715,0.000002169332],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955231,0.0006240988,0.002444202,0.00004527519,0.000006409592,0.00001366045,0.0001091799,0.00003999383,0.001194073],"genre_scores_gemma":[0.9946253,0.0006458753,0.00230016,0.00003561005,0.00001310926,0.00001757011,0.0003400721,0.00001517851,0.00200699],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001464817,"threshold_uncertainty_score":0.004900277,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009222819131380953,"score_gpt":0.2186719338553859,"score_spread":0.2094491147240049,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}