{"id":"W1985705246","doi":"10.2741/1862","title":"Serpins, the vasculature, and viral therapeutics","year":2006,"lang":"en","type":"review","venue":"Frontiers in bioscience","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"Robarts Clinical Trials","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Serpin; Proteases; Plasminogen activator; Urokinase receptor; Myxoma virus; Plasminogen activator inhibitor-1; Serine protease; Cell biology; Biology; Inflammation; Protease; Chemistry; Receptor; Immunology; Biochemistry; Virus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002931751,0.0002468691,0.0003712868,0.00007022648,0.0001081512,0.00005958174,0.0004770276,0.0003281471,6.334376e-7],"category_scores_gemma":[0.00001751616,0.0001534175,0.0001512005,0.0002148863,0.0002642978,0.000005191309,0.0001709529,0.000222506,0.00000163119],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002242913,"about_ca_system_score_gemma":0.0001339722,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009548196,"about_ca_topic_score_gemma":0.000004952494,"domain_scores_codex":[0.9987639,0.0001085873,0.0002242595,0.0004722622,0.0001533164,0.000277742],"domain_scores_gemma":[0.9994053,0.000005262775,0.0001098656,0.0004248417,0.00001700552,0.00003776549],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000005888173,0.00004475693,0.00006100076,0.0007656454,0.00005391735,0.000006127245,0.00001458927,7.99531e-7,0.0009874798,0.0002823263,0.01445706,0.9833204],"study_design_scores_gemma":[0.00007416133,0.00005269413,0.000007585421,0.0003495712,0.00006060191,0.00001453798,0.000006616456,0.00001728993,0.0007309804,0.0003131517,0.9981551,0.0002177618],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000453041,0.996857,0.001513365,0.00002349423,0.000809456,0.000421408,0.0000248675,0.000006630083,0.0002984388],"genre_scores_gemma":[0.0001087675,0.9972035,0.00172145,0.0002530584,0.0002146891,0.00004266272,0.00004794653,0.00001958142,0.0003883311],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.983698,"threshold_uncertainty_score":0.6256185,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01655179110688575,"score_gpt":0.2770567838373755,"score_spread":0.2605049927304897,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}