{"id":"W1985705246","doi":"10.2741/1862","title":"Serpins, the vasculature, and viral therapeutics","year":2006,"lang":"en","type":"review","venue":"Frontiers in bioscience","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"Robarts Clinical Trials","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Serpin; Proteases; Plasminogen activator; Urokinase receptor; Myxoma virus; Plasminogen activator inhibitor-1; Serine protease; Cell biology; Biology; Inflammation; Protease; Chemistry; Receptor; Immunology; Biochemistry; Virus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005783309,0.00026743,0.0002599724,0.0005386847,0.000239897,0.001204521,0.0003071457,0.0008438778,0.002443733],"category_scores_gemma":[0.0004603081,0.00009506418,0.0001593755,0.0002737665,0.0008829672,0.000980288,0.0005738362,0.001767236,0.0008812836],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006224437,"about_ca_system_score_gemma":0.0005041353,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005216164,"about_ca_topic_score_gemma":0.0007913155,"domain_scores_codex":[0.9997886,0.00005827455,0.00001168438,0.00002852774,0.0000760253,0.00003688287],"domain_scores_gemma":[0.9998547,0.0000319938,0.00002735844,0.00001070249,0.00003242321,0.00004280345],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004745819,0.0002658486,0.0009814972,0.001605374,0.00005952383,0.000759149,0.0002541076,0.0009593596,0.06483664,0.1505199,0.05942848,0.7198554],"study_design_scores_gemma":[0.0000531469,0.0006156015,0.001466082,0.000541673,0.00002872956,0.001431547,0.0001228272,0.0005543476,0.01335425,0.02836955,0.9534375,0.00002467434],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01489879,0.9248459,0.004850508,0.01874934,0.00375697,0.00003149013,0.0001213704,0.0001540026,0.03259157],"genre_scores_gemma":[0.1957327,0.7482687,0.004151437,0.00895447,0.005718579,0.00009683747,0.0002027401,0.00005376849,0.03682078],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002443733,"threshold_uncertainty_score":0.008175075,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01655179110688575,"score_gpt":0.2770567838373755,"score_spread":0.2605049927304897,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}