{"id":"W1985713600","doi":"10.1126/stke.12pe2","title":"Notch and Integrin Affinity: A Sticky Situation","year":2008,"lang":"en","type":"review","venue":"Science Signaling","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Notch signaling pathway; Cell biology; Notch proteins; Integrin; Hes3 signaling axis; Vitronectin; Biology; Hairless; Signal transduction; Cell fate determination; Effector; Cell adhesion; Cell; Fibronectin; Extracellular matrix; Transcription factor; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008855761,0.001028588,0.001837127,0.001165477,0.0005677606,0.002035492,0.00168626,0.002981665,0.00331928],"category_scores_gemma":[0.0008383812,0.0004998373,0.0003405394,0.001434575,0.002222969,0.004624957,0.001403602,0.00370713,0.002860891],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001427915,"about_ca_system_score_gemma":0.0006716954,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009723665,"about_ca_topic_score_gemma":0.001320454,"domain_scores_codex":[0.9996594,0.00006209713,0.00003958768,0.00008475255,0.0001237982,0.00003040321],"domain_scores_gemma":[0.9997304,0.0001278606,0.00002419947,0.00001662921,0.00006801372,0.00003288276],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000147976,0.00003168908,0.0001863425,0.005375566,0.00008782039,0.0006235001,0.0003007451,0.0006265932,0.005211527,0.06230127,0.07146754,0.8536395],"study_design_scores_gemma":[0.00001126982,0.00003680825,0.0001997968,0.0006031645,0.00002445299,0.0008774757,0.00009011228,0.00005888756,0.0004949902,0.01557114,0.9820181,0.00001374543],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001754368,0.9944343,0.0004317434,0.001813432,0.0007400265,0.000002314944,0.000009138115,0.000008392894,0.002385212],"genre_scores_gemma":[0.002151705,0.9910256,0.0003864655,0.001633594,0.0009415437,0.000008436491,0.00001615273,0.000004297639,0.003832222],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00331928,"threshold_uncertainty_score":0.01110417,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03247526826270861,"score_gpt":0.3218376982918856,"score_spread":0.289362430029177,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}