{"id":"W1985775190","doi":"10.1016/j.bbadis.2010.06.017","title":"Disruption of central nervous system barriers in multiple sclerosis","year":2010,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","topic":"Barrier Structure and Function Studies","field":"Neuroscience","cited_by":334,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Hôpital Notre-Dame","funders":"","keywords":"Experimental autoimmune encephalomyelitis; Multiple sclerosis; Blood–brain barrier; Central nervous system; Immune system; Neuroscience; Biology; Pathology; Immunology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001496685,0.0007966609,0.001971979,0.0004716764,0.0001396467,0.00005837515,0.0008062681,0.000368833,0.00001439288],"category_scores_gemma":[0.0007752969,0.000687893,0.001392536,0.001031319,0.0005536926,0.0001664425,0.0003235627,0.0005871721,0.00000953493],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000109873,"about_ca_system_score_gemma":0.0004848036,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004275045,"about_ca_topic_score_gemma":0.000005268585,"domain_scores_codex":[0.9957479,0.000613605,0.001180117,0.001141273,0.0007149409,0.0006021817],"domain_scores_gemma":[0.9968082,0.0002409346,0.001105516,0.001179751,0.00009724711,0.0005683833],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005751254,0.0006710126,0.00002642667,0.03531708,0.0004119734,0.0000850022,0.0004023209,0.00001155678,0.8534046,0.00179431,0.0001864534,0.1071142],"study_design_scores_gemma":[0.002766866,0.0004595071,0.005391318,0.02825835,0.006399902,0.00001916263,0.0003218695,0.0001728132,0.921955,0.0001209335,0.03071294,0.003421375],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5354062,0.4553033,0.00008315399,0.0001828074,0.001536413,0.002678598,0.00436153,0.0001972663,0.0002507177],"genre_scores_gemma":[0.6555634,0.3439356,0.00005926261,0.00007350365,0.00007611237,0.0001183537,0.00008423535,0.00008277997,0.000006791764],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1201572,"threshold_uncertainty_score":0.9995572,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04223845211617797,"score_gpt":0.2751515618260183,"score_spread":0.2329131097098403,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}