{"id":"W1985781751","doi":"10.1371/journal.pone.0117306","title":"Skeletal Muscle Fibrosis in the mdx/utrn+/- Mouse Validates Its Suitability as a Murine Model of Duchenne Muscular Dystrophy","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Duchenne muscular dystrophy; mdx mouse; Dystrophin; Utrophin; Fibrosis; Internal medicine; Medicine; Gastrocnemius muscle; Endocrinology; Diaphragm (acoustics); Muscular dystrophy; Hindlimb; Skeletal muscle; Pathology; Anatomy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006312245,0.0006683395,0.0005324538,0.001441,0.0004406086,0.0004217936,0.0003450265,0.0006887521,0.002865281],"category_scores_gemma":[0.0002877174,0.0003520746,0.0003480711,0.0003119986,0.0005226546,0.0004727739,0.0003746926,0.0008627524,0.0006771329],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002710499,"about_ca_system_score_gemma":0.0001703936,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008401149,"about_ca_topic_score_gemma":0.002045577,"domain_scores_codex":[0.9992976,0.0001026061,0.000130974,0.0002251385,0.0001548045,0.00008886427],"domain_scores_gemma":[0.9993544,0.0001003312,0.0001951095,0.00009419722,0.00009048695,0.0001653307],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001787075,0.00008926155,0.0007651594,0.00004378284,0.00000518349,0.0001010401,0.00003473017,0.00003191551,0.9979219,0.00009724297,0.00003443661,0.0006966799],"study_design_scores_gemma":[0.00008053363,0.002415586,0.04770225,0.0001020937,0.00005817716,0.003508985,0.0001810963,0.001379107,0.9391787,0.0001479168,0.005221668,0.00002391953],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.98805,0.001738989,0.005732642,0.0001704529,0.00006329794,0.0001259529,0.001307458,0.0001487779,0.002662437],"genre_scores_gemma":[0.9619676,0.001974839,0.02133469,0.0001815608,0.00003345327,0.0003842301,0.00237028,0.0001347391,0.0116184],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002865281,"threshold_uncertainty_score":0.009585321,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04382902598086507,"score_gpt":0.2417590927291275,"score_spread":0.1979300667482624,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}