{"id":"W1985783262","doi":"10.1038/sj.ejhg.5201064","title":"A high frequency of BRCA2 gene mutations in Polish families with ovarian and stomach cancer","year":2003,"lang":"en","type":"article","venue":"European Journal of Human Genetics","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":false,"ca_institutions":"Coalition for Research in Women's Health","funders":"","keywords":"Ovarian cancer; Stomach cancer; Cancer; Penetrance; Family history; Stomach; BRCA2 Protein; Breast cancer; Oncology; Internal medicine; Population; Biology; Mutation; Germline mutation; Medicine; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003077751,0.0001252989,0.0001640698,0.0001372325,0.00005627911,0.00001991439,0.0001639635,0.00003176872,0.00002703118],"category_scores_gemma":[0.00003475802,0.0001144409,0.0000381323,0.0001351692,0.0001685952,0.000005647788,0.00002986028,0.0001195439,5.353007e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003485287,"about_ca_system_score_gemma":0.0002272384,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002813105,"about_ca_topic_score_gemma":0.000204507,"domain_scores_codex":[0.998903,0.0002282079,0.00041753,0.0001584637,0.000145149,0.0001476536],"domain_scores_gemma":[0.9991916,0.000008276595,0.0002948299,0.0001969358,0.0002409818,0.00006737396],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005014595,0.0001336524,0.07811063,0.00003858396,0.000234694,0.0000916785,0.00157855,0.006782741,0.9085092,0.0005291564,0.0003968752,0.003544093],"study_design_scores_gemma":[0.004845625,0.002042942,0.4837641,0.0001495324,0.0002009794,0.0004779694,0.001453812,0.0000127657,0.5021217,0.000639976,0.003748812,0.000541733],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936681,0.004062376,0.0008165892,0.00005109051,0.000103099,0.0000773298,0.00002259699,0.000001948021,0.001196817],"genre_scores_gemma":[0.9835067,0.0006489121,0.01550717,0.00007370005,0.0001382841,0.00000208646,0.000008478304,0.00003522478,0.0000794],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4063874,"threshold_uncertainty_score":0.4666765,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01231056688916614,"score_gpt":0.2580554013507544,"score_spread":0.2457448344615882,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}