{"id":"W1985794991","doi":"10.1111/j.1537-2995.2009.02162.x","title":"The proximal cis‐regulatory region of the <i>RHD</i>/<i>RHCE</i> promoter is 105 bp and contains a 55‐bp core devoid of known binding motifs but necessary for transcription","year":2009,"lang":"en","type":"article","venue":"Transfusion","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Blood Services; University of Toronto; Mount Sinai Hospital","funders":"","keywords":"Promoter; Transcription factor; Transcription (linguistics); Biology; Gene; Electrophoretic mobility shift assay; Molecular biology; Genetics; Binding site; Regulatory sequence; Cis-regulatory module; Enhancer; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000262522,0.000187685,0.0003582326,0.00006606096,0.0002639425,0.000007187199,0.0001071503,0.000188434,0.00001947971],"category_scores_gemma":[0.00002011567,0.0001101941,0.0002153549,0.0001861494,0.0002417116,0.00008739159,0.00000929281,0.0002112209,0.000001079852],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000328805,"about_ca_system_score_gemma":0.00008869306,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002976142,"about_ca_topic_score_gemma":0.00004494067,"domain_scores_codex":[0.9987623,0.00007796069,0.0004114173,0.0002843148,0.0002306481,0.0002333771],"domain_scores_gemma":[0.9992143,0.00008400876,0.0001509734,0.0003286784,0.0001522723,0.00006976577],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003123758,0.0002026954,0.001595493,0.0003496375,0.00003538334,0.000002355536,0.002565107,0.000002782874,0.9734454,0.0004356145,0.001197841,0.01704391],"study_design_scores_gemma":[0.01443835,0.007183702,0.1039064,0.001481607,0.0008991862,0.0003573013,0.002020674,0.00205303,0.8483559,0.002317693,0.01648195,0.0005041425],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920689,0.0004995568,0.001380733,0.003842483,0.0002733869,0.001596003,0.00002855257,0.00003563443,0.0002747268],"genre_scores_gemma":[0.9971447,0.0007024028,0.0001555874,0.0009745443,0.0001151672,0.00002778653,0.00002075518,0.00002034979,0.0008386935],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1250895,"threshold_uncertainty_score":0.4493585,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0256883923775819,"score_gpt":0.2538573210592276,"score_spread":0.2281689286816457,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}