{"id":"W1985794991","doi":"10.1111/j.1537-2995.2009.02162.x","title":"The proximal cis‐regulatory region of the <i>RHD</i>/<i>RHCE</i> promoter is 105 bp and contains a 55‐bp core devoid of known binding motifs but necessary for transcription","year":2009,"lang":"en","type":"article","venue":"Transfusion","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Blood Services; University of Toronto; Mount Sinai Hospital","funders":"","keywords":"Promoter; Transcription factor; Transcription (linguistics); Biology; Gene; Electrophoretic mobility shift assay; Molecular biology; Genetics; Binding site; Regulatory sequence; Cis-regulatory module; Enhancer; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001578359,0.0003948016,0.0003230553,0.0001982917,0.0001721684,0.0002678592,0.000254658,0.0002796337,0.002027023],"category_scores_gemma":[0.0002566959,0.0001999471,0.0003116561,0.000118502,0.0004793628,0.0001317438,0.0002410353,0.0005746186,0.00146774],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003846051,"about_ca_system_score_gemma":0.0004449106,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005613505,"about_ca_topic_score_gemma":0.0004075888,"domain_scores_codex":[0.9997576,0.00002645526,0.00001960983,0.0001009332,0.00005902513,0.000036361],"domain_scores_gemma":[0.9997434,0.00005730769,0.00009548591,0.00002929417,0.00002787515,0.00004662113],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001191701,0.00002121387,0.0009528387,0.00005434118,0.00000330454,0.00007124875,0.00002316024,0.00006079345,0.9962794,0.0001952989,0.00006449292,0.002154669],"study_design_scores_gemma":[0.00002697947,0.0001353742,0.01308126,0.00003089545,0.00002046187,0.001321519,0.00004326131,0.000702114,0.9774606,0.0001481648,0.007019249,0.000009983502],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9441438,0.003005461,0.04470734,0.0003284239,0.00006592819,0.0001823006,0.002966395,0.0004567673,0.004143551],"genre_scores_gemma":[0.9657214,0.0009047966,0.02622076,0.0001068934,0.00003323056,0.0001470269,0.004262278,0.00007886739,0.00252468],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002027023,"threshold_uncertainty_score":0.006781101,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0256883923775819,"score_gpt":0.2538573210592276,"score_spread":0.2281689286816457,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}