{"id":"W1985795036","doi":"10.4161/cc.9.3.10552","title":"Protecting the hedgerow: p53 and Hedgehog pathway interactions","year":2010,"lang":"en","type":"review","venue":"Cell Cycle","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"","keywords":"Biology; Hedgehog; Hedgehog signaling pathway; Suppressor; Subfamily; Cell biology; Cancer research; Carcinogenesis; Signal transduction; Genetics; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004477494,0.0003691248,0.0005389203,0.00004857242,0.0005438947,0.00007161176,0.0003165923,0.0003247205,0.00001474586],"category_scores_gemma":[0.0002823552,0.0002493016,0.0002742401,0.0001079067,0.0001655965,0.000002845891,0.0003660104,0.001017114,0.00006484517],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000162139,"about_ca_system_score_gemma":0.0001390362,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001028845,"about_ca_topic_score_gemma":0.00003569387,"domain_scores_codex":[0.998473,0.0002562497,0.0003461318,0.000529436,0.00009446207,0.0003006707],"domain_scores_gemma":[0.9988777,0.0001335401,0.0002410222,0.0006054462,0.00006238122,0.00007989536],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00000301201,0.0000338438,0.000002778529,0.002270815,0.00009084091,0.000004974529,0.0001779704,9.770348e-7,0.01066334,0.00000778569,0.0005948479,0.9861488],"study_design_scores_gemma":[0.00007670353,0.00004988216,0.000001368647,0.0006080184,0.0001201348,0.00005079075,0.00009221738,0.000002654854,0.005046991,0.00001366498,0.9936522,0.0002854021],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001277335,0.9931733,0.00009991819,0.00003736437,0.000557277,0.0007353104,0.00002982635,0.00002892443,0.004060752],"genre_scores_gemma":[0.002183243,0.9937015,0.0001715632,0.0000549553,0.001176441,0.0002956726,0.00006842837,0.00008398054,0.00226418],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9930573,"threshold_uncertainty_score":0.9999959,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02954836961588529,"score_gpt":0.303927713575343,"score_spread":0.2743793439594577,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}