{"id":"W1985999015","doi":"10.1182/blood-2011-06-361626","title":"Ionizing radiation–induced expression of INK4a/ARF in murine bone marrow–derived stromal cell populations interferes with bone marrow homeostasis","year":2011,"lang":"en","type":"article","venue":"Blood","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer; Centre Hospitalier Universitaire Sainte-Justine","funders":"Canadian Institutes of Health Research","keywords":"Stromal cell; Bone marrow; Haematopoiesis; Lymphopoiesis; Cancer research; Biology; Senescence; Stem cell; Cell biology; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002861889,0.0003294795,0.0002707601,0.0003091522,0.0001308312,0.0002946095,0.0001922623,0.0001886148,0.001139392],"category_scores_gemma":[0.0001379003,0.0001421598,0.000255266,0.0001577965,0.0002327949,0.0001083595,0.0002225952,0.0005737604,0.0003475631],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001460204,"about_ca_system_score_gemma":0.0001193778,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001670083,"about_ca_topic_score_gemma":0.0002796678,"domain_scores_codex":[0.9997072,0.00008130374,0.0000370276,0.00004716439,0.00006838011,0.00005883457],"domain_scores_gemma":[0.9998372,0.00003480307,0.00004561324,0.00003843812,0.000009472528,0.00003452926],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008983955,0.0000206952,0.0001046269,0.000009401184,0.000002847354,0.00001715917,0.00001043115,0.00002343627,0.9991218,0.00003693843,0.00000752653,0.0005552748],"study_design_scores_gemma":[0.00001190866,0.0003014366,0.00161132,0.000002465503,0.00001015836,0.0001090946,0.00001257732,0.0003117223,0.996738,0.0000192475,0.00087067,0.000001570705],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960614,0.0009106612,0.00213388,0.00003163452,0.00001364105,0.0000202372,0.0001317557,0.00005440618,0.0006423748],"genre_scores_gemma":[0.9944562,0.0006178797,0.002208056,0.00003474601,0.00001369237,0.00006964836,0.0004593158,0.00003094898,0.002109405],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001139392,"threshold_uncertainty_score":0.003811657,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0411318214147731,"score_gpt":0.2483351379391451,"score_spread":0.207203316524372,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}