{"id":"W1985999816","doi":"10.1016/s0264-410x(03)00172-5","title":"Effective induction of CD8+ T-cell response using CpG oligodeoxynucleotides and HER-2/neu-derived peptide co-encapsulated in liposomes","year":2003,"lang":"en","type":"article","venue":"Vaccine","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":69,"is_retracted":false,"has_abstract":false,"ca_institutions":"Celator Pharmaceuticals (Canada); University of British Columbia; BC Cancer Agency","funders":"","keywords":"ELISPOT; CpG Oligodeoxynucleotide; Adjuvant; CTL*; Antigen; CpG site; Liposome; Cytotoxic T cell; Splenocyte; Immunology; Molecular biology; Biology; CD8; Chemistry; Biochemistry; In vitro; DNA methylation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007498008,0.0002346812,0.0004580541,0.0003859572,0.0001333651,0.00001154959,0.0001033923,0.0002659039,0.0002656965],"category_scores_gemma":[0.000333974,0.0002142311,0.00007193696,0.0003326386,0.0000753951,0.000168181,0.0000305832,0.0003041231,0.00003004384],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006096935,"about_ca_system_score_gemma":0.00007377313,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002531753,"about_ca_topic_score_gemma":0.00001153114,"domain_scores_codex":[0.9975172,0.001407366,0.0004267198,0.0002925036,0.00003312208,0.0003230553],"domain_scores_gemma":[0.9989437,0.0005003751,0.0001945725,0.0002732856,0.00007135153,0.00001672862],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006681023,0.0001976181,0.006536179,0.00002914472,0.0001160582,0.000006502527,0.0009927195,0.0000472261,0.9843874,0.0000423639,0.00005958053,0.0009042065],"study_design_scores_gemma":[0.00441356,0.0005631667,0.1280876,0.00009280802,0.00003156557,0.0001233602,0.000554844,0.000008966147,0.8640716,0.00006119037,0.00179453,0.0001968464],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9899447,0.009118309,0.00003663929,0.00005956229,0.0002486555,0.0004307607,0.000008803119,0.00003794154,0.0001146453],"genre_scores_gemma":[0.9986699,0.00042227,0.0001499666,0.00004805067,0.000006426262,0.00001847584,0.00001105105,0.00002915375,0.0006447703],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1215514,"threshold_uncertainty_score":0.8736091,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0107505508461909,"score_gpt":0.2478563150503803,"score_spread":0.2371057642041894,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}