{"id":"W1986000961","doi":"10.1111/j.1468-3083.2005.01212.x","title":"A phase I/II randomized, double‐blind, placebo‐controlled, dose‐ranging study evaluating the efficacy, safety and pharmacokinetics of ravuconazole in the treatment of onychomycosis","year":2005,"lang":"en","type":"article","venue":"Journal of the European Academy of Dermatology and Venereology","topic":"Nail Diseases and Treatments","field":"Medicine","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Mediprobe Research (Canada); Sunnybrook Health Science Centre","funders":"","keywords":"Medicine; Placebo; Adverse effect; Dosing; Dose-ranging study; Pharmacokinetics; Randomized controlled trial; Surgery; Nail disease; Double blind; Clinical trial; Internal medicine; Complication; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001669651,0.0001880785,0.001212682,0.0001612509,0.0001297543,0.000003695078,0.0002285087,0.00006464014,0.00001331534],"category_scores_gemma":[0.0001350057,0.00008131559,0.0003117434,0.0001344305,0.0004909363,0.00003985196,0.0000737727,0.0002900969,5.047804e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000198037,"about_ca_system_score_gemma":0.00004669758,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006230941,"about_ca_topic_score_gemma":0.000002121606,"domain_scores_codex":[0.9958471,0.002431542,0.001180516,0.0001362864,0.0002182721,0.0001862601],"domain_scores_gemma":[0.9973004,0.001331457,0.001103512,0.0001467234,0.00005767117,0.00006019892],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8939376,0.009315871,0.05241013,0.00007673369,0.00347801,0.0001181918,0.007411209,0.0004293264,0.001397224,0.0003325235,0.00006688741,0.03102633],"study_design_scores_gemma":[0.9683553,0.001706367,0.02002284,0.0001112042,0.004591485,0.001955627,0.0006079761,0.000946763,0.001063841,0.0000630354,0.0004992678,0.0000763099],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9807254,0.0101479,0.00001015719,0.007168725,0.00006599099,0.001440386,0.000005148822,0.000002220886,0.0004340783],"genre_scores_gemma":[0.9964597,0.0030316,0.00007477393,0.0002676014,0.0001017625,0.00001045988,8.531479e-7,0.00001218536,0.00004102579],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07441772,"threshold_uncertainty_score":0.3315954,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04845389368191447,"score_gpt":0.3866937521226771,"score_spread":0.3382398584407627,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}