{"id":"W1986014495","doi":"10.1016/j.jim.2011.12.004","title":"Suppression of protein phosphatase 2A activity enhances Ad5/F35 adenovirus transduction efficiency in normal human B lymphocytes and in Raji cells","year":2011,"lang":"en","type":"article","venue":"Journal of Immunological Methods","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; Héma-Québec","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Protein phosphatase 2; Biology; Phosphatase; Transduction (biophysics); Raji cell; Intracellular; Cell biology; Molecular biology; Signal transduction; Okadaic acid; Phosphorylation; Cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001047556,0.0005691273,0.0004967976,0.00106424,0.0003714485,0.0009030557,0.0005171043,0.0004169881,0.001793151],"category_scores_gemma":[0.0005012366,0.0003505992,0.0005167112,0.0005230739,0.0006469467,0.0005389652,0.0004835579,0.001334841,0.0007473251],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006745206,"about_ca_system_score_gemma":0.0004682986,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00273965,"about_ca_topic_score_gemma":0.001462152,"domain_scores_codex":[0.9990883,0.0002897239,0.000111796,0.0001093102,0.0002167144,0.0001841137],"domain_scores_gemma":[0.9994235,0.0002608356,0.00005300775,0.0001140849,0.00005779256,0.00009081369],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000138185,0.00005794482,0.0001819272,0.00002367135,0.000005578552,0.00002714097,0.00005101771,0.00004368077,0.9988556,0.0002128564,0.00001736299,0.0003849706],"study_design_scores_gemma":[0.00001249023,0.0001975643,0.001364264,0.000002647577,0.00001498531,0.000103408,0.00003251454,0.0007968366,0.9967011,0.00003304569,0.000737277,0.000003968379],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932501,0.00134405,0.003593988,0.00005480342,0.00002994204,0.00005476523,0.0003670655,0.0001504008,0.001154754],"genre_scores_gemma":[0.9936986,0.0005301861,0.002640046,0.00001595889,0.0000134235,0.0000500742,0.0005919269,0.00003656735,0.002423201],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00273965,"threshold_uncertainty_score":0.005998671,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04249440235927551,"score_gpt":0.3617924025623843,"score_spread":0.3192980002031088,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}