{"id":"W1986063675","doi":"10.1021/ic800775w","title":"Expedient Multi-Step Synthesis of Organometallic Complexes of Tc and Re in High Effective Specific Activity. A New Platform for the Production of Molecular Imaging and Therapy Agents","year":2008,"lang":"en","type":"article","venue":"Inorganic Chemistry","topic":"Radiopharmaceutical Chemistry and Applications","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Yield (engineering); Ligand (biochemistry); Combinatorial chemistry; Chelation; Rhenium; Molecular imaging; Extraction (chemistry); Imaging agent; Microwave irradiation; Solid phase extraction; Chromatography; Nanotechnology; Organic chemistry; Catalysis; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001973949,0.0003692567,0.0003119269,0.0001750769,0.0001029405,0.0002379107,0.0004701181,0.0003332375,0.001078578],"category_scores_gemma":[0.0002118573,0.0002253731,0.0002143974,0.0001597888,0.0001330901,0.0002750066,0.0003652653,0.0004774484,0.0007759202],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003237589,"about_ca_system_score_gemma":0.0003014981,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004619157,"about_ca_topic_score_gemma":0.001033374,"domain_scores_codex":[0.9998559,0.00001852071,0.00001406855,0.00003623645,0.00004764791,0.0000276328],"domain_scores_gemma":[0.9999235,0.000009710873,0.00002512425,0.00001027349,0.00001655308,0.00001485499],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004658777,0.00001538347,0.00002851688,0.0001100306,0.000008947607,0.0000608077,0.0000204366,0.0002575604,0.9944993,0.0004065568,0.00009947875,0.004446414],"study_design_scores_gemma":[0.00003025019,0.000206415,0.0001686314,0.000004647019,0.00001647428,0.0002083948,0.000007887878,0.0008746115,0.9914374,0.00008692531,0.006949259,0.000009168537],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.7803205,0.01061036,0.1846329,0.0003169077,0.0002058813,0.0008118707,0.0009572229,0.001806678,0.02033779],"genre_scores_gemma":[0.8987154,0.002870246,0.08821661,0.0001057483,0.00003091939,0.0002217968,0.0004722716,0.0001368251,0.009230105],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.001078578,"threshold_uncertainty_score":0.003608167,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04217531888791921,"score_gpt":0.2984968412334751,"score_spread":0.2563215223455559,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}