{"id":"W1986093701","doi":"10.1038/sj.leu.2402455","title":"Pharmacokinetic interactions of cyclosporine with etoposide and mitoxantrone in children with acute myeloid leukemia","year":2002,"lang":"en","type":"article","venue":"Leukemia","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":false,"ca_institutions":"Pediatric Oncology Group","funders":"National Center for Research Resources; National Cancer Institute; National Institutes of Health","keywords":"Mitoxantrone; Etoposide; Pharmacokinetics; Pharmacology; Medicine; Myeloid leukemia; Cytarabine; Toxicity; Chemotherapy; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007064493,0.0003201758,0.0008836928,0.0002860239,0.0003533899,0.0005193662,0.0002275234,0.0004052443,0.0005223979],"category_scores_gemma":[0.004356273,0.0001949471,0.0004900633,0.0004496308,0.0003370935,0.0005018038,0.0002408214,0.001122626,0.0001271673],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00118149,"about_ca_system_score_gemma":0.0008800602,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003396756,"about_ca_topic_score_gemma":0.003752854,"domain_scores_codex":[0.9993346,0.0003427377,0.00004543163,0.00005405358,0.0001515192,0.00007156976],"domain_scores_gemma":[0.998324,0.0008134172,0.0004890928,0.0000419821,0.00009843545,0.0002330982],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.03903592,0.001031679,0.8053962,0.000472469,0.001057458,0.005544531,0.001308791,0.00848806,0.03683175,0.00097931,0.002576686,0.09727721],"study_design_scores_gemma":[0.0017372,0.02012342,0.9155179,0.00008521576,0.001402735,0.01677117,0.0008853596,0.009155872,0.02289485,0.0003230954,0.01103866,0.00006448184],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963554,0.002530398,0.0002857579,0.0001757517,0.00001596443,0.00001507097,0.00008963182,0.00002256293,0.0005094369],"genre_scores_gemma":[0.9987207,0.0006494204,0.0003116123,0.00005651124,0.00002681905,0.00001007275,0.00007765236,0.00000867114,0.000138514],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003396756,"threshold_uncertainty_score":0.00857228,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006500770798625346,"score_gpt":0.2255509247561506,"score_spread":0.2190501539575252,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}