{"id":"W1986124459","doi":"10.1016/s0197-0186(01)00004-3","title":"MKP-1 as a target for pharmacological manipulations in PC12 cell survival","year":2001,"lang":"en","type":"article","venue":"Neurochemistry International","topic":"Vanadium and Halogenation Chemistry","field":"Chemistry","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"MAPK/ERK pathway; Kinase; Dephosphorylation; Phosphorylation; Cell biology; Protein kinase A; p38 mitogen-activated protein kinases; Phosphatase; Protein tyrosine phosphatase; Mitogen-activated protein kinase; Biology; Dual-specificity phosphatase; Cancer research; Chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001866848,0.0004161419,0.0004306201,0.0002915201,0.0004534268,0.0005734004,0.0005457985,0.0004114925,0.001383745],"category_scores_gemma":[0.000139744,0.0002114998,0.0003377963,0.000366653,0.0003789391,0.0004450572,0.0003013696,0.001153587,0.0003476224],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000766643,"about_ca_system_score_gemma":0.0005251885,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001880982,"about_ca_topic_score_gemma":0.004047026,"domain_scores_codex":[0.9998566,0.00001666564,0.000009971543,0.00003141564,0.00002891276,0.00005628195],"domain_scores_gemma":[0.9999491,0.00001287007,0.000009564241,0.000006549359,0.00000819254,0.00001377223],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004302828,0.00003100238,0.00007118531,0.00008652513,0.000008966555,0.00008632692,0.00003693359,0.0001126909,0.9955053,0.0005324293,0.0001137794,0.002984397],"study_design_scores_gemma":[0.00001729917,0.0001406882,0.0004493936,0.000004265572,0.00001376805,0.00008018051,0.00002390106,0.0002361422,0.9972102,0.00008635707,0.00173433,0.000003327106],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9768544,0.006729147,0.008990007,0.000655195,0.0001635781,0.00007623901,0.0008427039,0.0002770601,0.005411704],"genre_scores_gemma":[0.987294,0.002960588,0.004620287,0.00006655855,0.00001617324,0.00006280543,0.0004182537,0.00004866668,0.004512731],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001880982,"threshold_uncertainty_score":0.005562484,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03101334131979574,"score_gpt":0.3051268335321148,"score_spread":0.2741134922123191,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}