{"id":"W1986190220","doi":"10.1016/j.bpj.2014.11.2046","title":"The Membrane Catalysis Model: Apelin and its Receptor","year":2015,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Apelin-related biomedical research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Apelin; Receptor; Chemistry; Biophysics; Membrane; Gene isoform; Peptide; Biochemistry; G protein-coupled receptor; Förster resonance energy transfer; Ligand (biochemistry); Cell biology; Biology; Fluorescence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007347777,0.001046965,0.001692584,0.0005645001,0.000991097,0.002600534,0.003943073,0.003825925,0.01377737],"category_scores_gemma":[0.001185976,0.0004496556,0.001063604,0.0004800206,0.0016963,0.005680335,0.001563539,0.002242234,0.00567222],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009022906,"about_ca_system_score_gemma":0.0009105362,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008795144,"about_ca_topic_score_gemma":0.0002654496,"domain_scores_codex":[0.9996982,0.00007635788,0.00001540467,0.00006652739,0.00006385466,0.00007969991],"domain_scores_gemma":[0.9996563,0.0001411497,0.00002748695,0.00006187042,0.00005032236,0.00006284965],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.00012548,0.00004757547,0.0001047337,0.0001762153,0.00002719739,0.0003786845,0.0001066441,0.008358887,0.009373248,0.9759128,0.002076723,0.003311861],"study_design_scores_gemma":[0.0001309813,0.0001048383,0.0001398937,0.00003604629,0.00003848454,0.0003635722,0.0001472581,0.1186792,0.002866759,0.8715625,0.005892154,0.00003830863],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.2756897,0.01614235,0.3930464,0.06183222,0.004257844,0.0003103805,0.001090356,0.0008057233,0.2468251],"genre_scores_gemma":[0.9213271,0.006381559,0.01668839,0.00216673,0.001066907,0.0003254022,0.0004396864,0.0001490066,0.05145512],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01377737,"threshold_uncertainty_score":0.04608989,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04863753271303782,"score_gpt":0.333539997023944,"score_spread":0.2849024643109062,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}