{"id":"W1986198140","doi":"10.1371/journal.pone.0028125","title":"TRAF6 and IRF7 Control HIV Replication in Macrophages","year":2011,"lang":"en","type":"article","venue":"PLoS ONE","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université Laval","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; Center for AIDS Research, University of Washington; University of California, San Diego; National Institutes of Health; Agence Nationale de la Recherche; Styrelsen för Internationellt Utvecklingssamarbete","keywords":"IRF7; IRF3; Viral replication; Innate immune system; Biology; Interferon regulatory factors; Virology; Interferon; Virus; Cell biology; Immune system; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002306474,0.0003154625,0.0001931876,0.0002547481,0.0002863008,0.0004786827,0.0002411852,0.0004190393,0.001243028],"category_scores_gemma":[0.0001611154,0.0001680636,0.000257018,0.0001003212,0.0002840764,0.0003279549,0.0002444413,0.0005570968,0.0007278003],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003440578,"about_ca_system_score_gemma":0.0002756707,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002883584,"about_ca_topic_score_gemma":0.0003928025,"domain_scores_codex":[0.999803,0.00003694444,0.00001260647,0.00002994812,0.00004948599,0.0000680781],"domain_scores_gemma":[0.9999025,0.00001091412,0.00002297375,0.00001266915,0.00002212499,0.00002871415],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003310832,0.00002826108,0.0004107156,0.00004060772,0.000004668723,0.00005987894,0.00002963436,0.000103151,0.9950559,0.000403289,0.00008104293,0.003451811],"study_design_scores_gemma":[0.00004718098,0.0002289661,0.005576071,0.00001175868,0.00002203264,0.0003837329,0.0001083102,0.001728333,0.985694,0.0006563147,0.005532554,0.00001059156],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9854357,0.006435975,0.004126592,0.0003526598,0.00006347915,0.00003558634,0.0002993265,0.0001102388,0.003140517],"genre_scores_gemma":[0.9922051,0.001619272,0.002267026,0.00004539709,0.00002179074,0.00003203064,0.0001773709,0.0000158458,0.003616194],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001243028,"threshold_uncertainty_score":0.004158318,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05031659436719789,"score_gpt":0.2377224114067221,"score_spread":0.1874058170395242,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}