{"id":"W1986214518","doi":"10.1074/jbc.m114.629899","title":"Osteoblast Menin Regulates Bone Mass in Vivo","year":2014,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Royal Victoria Hospital","funders":"Canadian Institutes of Health Research; McGill University Health Centre; McGill University","keywords":"Osteoblast; MEN1; Chemistry; Endocrinology; Osteoclast; Internal medicine; Cortical bone; Cell biology; Biology; In vitro; Anatomy; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001631964,0.0003425448,0.0003178447,0.0004879627,0.0001707829,0.0003442988,0.000161282,0.0002902292,0.001966298],"category_scores_gemma":[0.0001073789,0.0002012226,0.0001817467,0.0001484228,0.0002770487,0.0001762662,0.0002165158,0.0004026706,0.0005392822],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002983621,"about_ca_system_score_gemma":0.0001949105,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005302254,"about_ca_topic_score_gemma":0.001065021,"domain_scores_codex":[0.9998287,0.00001916702,0.00001053715,0.00004575314,0.00007212106,0.00002375419],"domain_scores_gemma":[0.9998056,0.00002092548,0.00006786223,0.00001562943,0.00002906247,0.00006096553],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001343208,0.00001372404,0.000239149,0.00001743373,0.000002800883,0.00003579435,0.000009964941,0.00002123119,0.998365,0.00005268805,0.00003790287,0.001069875],"study_design_scores_gemma":[0.00005958894,0.000429034,0.03337646,0.00001291554,0.00003762082,0.0004462216,0.00007966493,0.0004960115,0.9570886,0.0001631687,0.007803081,0.000007667065],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9825782,0.006817852,0.004604252,0.0002365766,0.00008905343,0.00003455323,0.0007543882,0.0001880158,0.004697125],"genre_scores_gemma":[0.9810463,0.003152783,0.001750319,0.000132609,0.00004209451,0.00003703897,0.0008302794,0.00007186569,0.01293666],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001966298,"threshold_uncertainty_score":0.006577909,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00954206481502507,"score_gpt":0.2316440581748386,"score_spread":0.2221019933598135,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}