{"id":"W1986268987","doi":"10.1016/j.jdermsci.2008.07.009","title":"Development of an in vitro psoriatic skin model by tissue engineering","year":2008,"lang":"en","type":"article","venue":"Journal of Dermatological Science","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":127,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hôpital de l'Enfant-Jésus; Université Laval; Hôpital du Saint-Sacrement","funders":"","keywords":"Involucrin; Psoriasis; Dermis; Immunohistochemistry; Loricrin; Pathology; Epidermis (zoology); Filaggrin; Human skin; Medicine; Keratinocyte; Extracellular matrix; Dermatology; In vitro; Chemistry; Biology; Anatomy; Atopic dermatitis; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007027994,0.0007203999,0.0004708058,0.000615976,0.0003788136,0.0006785105,0.0006769091,0.0006267506,0.002147257],"category_scores_gemma":[0.0003113354,0.0004191697,0.0007143895,0.0002538491,0.0002618186,0.0005212416,0.0003441108,0.002154201,0.001298098],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002518664,"about_ca_system_score_gemma":0.0002889961,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004696502,"about_ca_topic_score_gemma":0.0007818837,"domain_scores_codex":[0.9995459,0.0001120023,0.00006115632,0.00006856628,0.0001528574,0.00005950413],"domain_scores_gemma":[0.9995432,0.0001202214,0.00006980325,0.0001215692,0.00006210909,0.00008313224],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004100737,0.00007464654,0.00004326869,0.00004232123,0.000003652281,0.00007944166,0.00001771837,0.0001038933,0.9985059,0.0001924564,0.00004230456,0.0008532958],"study_design_scores_gemma":[0.00001507943,0.0002626793,0.0003869363,0.000009517067,0.00002676131,0.0002976265,0.00002033356,0.001097257,0.9957708,0.0000606737,0.002048584,0.000003851261],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8176763,0.004479013,0.1530976,0.0006659841,0.0009311045,0.0009524344,0.001751959,0.0009304007,0.0195153],"genre_scores_gemma":[0.9255651,0.002782058,0.06054271,0.0002201562,0.00009873864,0.0004516243,0.001204056,0.0001466216,0.008988944],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002147257,"threshold_uncertainty_score":0.007183313,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02023604454409368,"score_gpt":0.2446566719822383,"score_spread":0.2244206274381446,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}