{"id":"W1986271539","doi":"10.1152/ajpendo.00254.2012","title":"Defective postnatal endochondral bone development by chondrocyte-specific targeted expression of parathyroid hormone type 2 receptor","year":2012,"lang":"en","type":"article","venue":"American Journal of Physiology-Endocrinology and Metabolism","topic":"Bone health and treatments","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital; McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Chondrocyte; Endochondral ossification; Internal medicine; Endocrinology; Biology; Parathyroid hormone; Parathyroid hormone receptor; Receptor; Chondrogenesis; Bone growth; Parathyroid hormone-related protein; Ossification; Immunostaining; SOX9; Indian hedgehog; Cell biology; Genetically modified mouse; Transgene; Cartilage; Anatomy; Gene expression; Immunohistochemistry; Medicine; Hormone receptor; Calcium; Stem cell; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001886003,0.0006872509,0.0004202189,0.0006128694,0.0001503968,0.00031702,0.0004834834,0.0005584613,0.002947794],"category_scores_gemma":[0.0001764315,0.0003827094,0.0004777113,0.000163857,0.0004377248,0.0001876365,0.0003421346,0.0007339987,0.0008067075],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002682492,"about_ca_system_score_gemma":0.0003703041,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001012843,"about_ca_topic_score_gemma":0.001287537,"domain_scores_codex":[0.9996572,0.00003054436,0.00004235669,0.00009052101,0.0001290296,0.00005044359],"domain_scores_gemma":[0.9997054,0.00003777865,0.0001160273,0.00003690843,0.00002067522,0.00008323253],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004851331,0.00001579824,0.00007716881,0.00002003221,0.00000373512,0.0001477009,0.00000917999,0.00003504615,0.9990999,0.00008840489,0.00002027117,0.0004343899],"study_design_scores_gemma":[0.00005561433,0.0003096462,0.008823521,0.00001873958,0.00003902894,0.002544329,0.00004063836,0.001447999,0.9828398,0.00007745859,0.003791232,0.00001198223],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9867422,0.001592077,0.00784839,0.0001271442,0.00007373896,0.00006947471,0.001239471,0.000515674,0.001791788],"genre_scores_gemma":[0.9846935,0.001260356,0.003459498,0.00006144835,0.00001577751,0.0001040835,0.0009492416,0.000164224,0.009291987],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002947794,"threshold_uncertainty_score":0.00986141,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01111635482381253,"score_gpt":0.261161529151463,"score_spread":0.2500451743276505,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}