{"id":"W1986272680","doi":"10.1016/j.cjca.2014.01.018","title":"A Single Fixed-Dose Combination for All Patients Is Bad Medicine","year":2014,"lang":"en","type":"review","venue":"Canadian Journal of Cardiology","topic":"Medication Adherence and Compliance","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"Canadian Institutes of Health Research","keywords":"Medicine; Polypill; Pill; Fixed-dose combination; Intensive care medicine; Internal medicine; Pharmacology; Aspirin","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000547472,0.000232233,0.002265064,0.0004600325,0.00005251564,0.000007662065,0.0002689648,0.0003393118,0.0002083898],"category_scores_gemma":[0.001038595,0.0001717633,0.0005020695,0.0001471878,0.0001774493,0.00003387697,0.000007021775,0.00038008,0.0001055917],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003173642,"about_ca_system_score_gemma":0.001953505,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006819904,"about_ca_topic_score_gemma":0.00003722719,"domain_scores_codex":[0.9982186,0.0001645451,0.0009072502,0.0001992349,0.0001955292,0.0003148734],"domain_scores_gemma":[0.9970608,0.0002212394,0.0008787298,0.0002969883,0.0007492515,0.0007930116],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001028857,0.000004780384,0.0001770929,0.001815752,0.0003000895,0.00001754146,0.00003612102,2.014815e-7,2.324881e-7,0.0001212682,0.3818966,0.6156201],"study_design_scores_gemma":[0.001460459,0.001361654,0.0001989322,0.006279814,0.001247684,0.000357244,0.00001015205,0.000001912323,2.282697e-7,0.0002067989,0.9887472,0.0001279083],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001703572,0.985797,0.00189235,0.001903086,0.001821814,0.0007882807,0.00004628675,0.000004847665,0.007729241],"genre_scores_gemma":[0.00118781,0.9908755,0.0001766886,0.002864287,0.002675782,0.00005205876,0.0003377449,0.00004721226,0.001782871],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.6154922,"threshold_uncertainty_score":0.7004304,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0965190345435896,"score_gpt":0.3578200860167511,"score_spread":0.2613010514731615,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}