{"id":"W1986278647","doi":"10.1007/s10689-011-9482-6","title":"Implications for cancer genetics practice of pro-actively assessing family history in a General Practice cohort in North West London","year":2011,"lang":"en","type":"article","venue":"Familial Cancer","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Cancer Research","funders":"National Institute for Health and Care Research; Cancer Research UK","keywords":"Family history; Medicine; Population; Referral; Genetic counseling; Breast cancer; Cancer; Epidemiology; Family medicine; Cohort; Incidence (geometry); Gynecology; Demography; Internal medicine; Genetics; Environmental health; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00742451,0.0002680831,0.0004610056,0.0009903144,0.002636974,0.003369719,0.001585821,0.002607484,0.009458154],"category_scores_gemma":[0.03110498,0.0003618925,0.0003661631,0.001094191,0.001797459,0.001430117,0.002676668,0.002021143,0.000903004],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004198516,"about_ca_system_score_gemma":0.01380866,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.1521644,"about_ca_topic_score_gemma":0.2196629,"domain_scores_codex":[0.994304,0.003032074,0.0006942935,0.0004689394,0.0007551871,0.0007454274],"domain_scores_gemma":[0.9680971,0.0116934,0.002963254,0.001221354,0.004772787,0.01125211],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002984029,0.0003756211,0.8830959,0.0006056438,0.00005854802,0.009206379,0.02126567,0.0003336957,0.001225319,0.002026235,0.0400326,0.0414761],"study_design_scores_gemma":[0.0003195318,0.0008307464,0.774895,0.002739024,0.0001489626,0.007725705,0.1545271,0.001153018,0.0004841897,0.004439239,0.05258216,0.0001554351],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5725821,0.004277341,0.001162873,0.3953162,0.001705145,0.0003006353,0.0004705329,0.00010149,0.02408366],"genre_scores_gemma":[0.9490672,0.002322371,0.002842827,0.03768047,0.0006611736,0.000322892,0.000158,0.00004411619,0.006900877],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1521644,"threshold_uncertainty_score":0.3025574,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05584658950717499,"score_gpt":0.350116635948711,"score_spread":0.294270046441536,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}