{"id":"W1986282241","doi":"10.1038/nm1565","title":"Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood","year":2007,"lang":"en","type":"article","venue":"Nature Medicine","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":2252,"is_retracted":false,"has_abstract":false,"ca_institutions":"Foothills Medical Centre; University of Calgary","funders":"","keywords":"Neutrophil extracellular traps; TLR4; Platelet; Sepsis; Extracellular; Immunology; Platelet activation; Pathogenesis; Bacteria; Septic shock; Microbiology; Biology; Cell biology; Inflammation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005861662,0.0005134825,0.0003192182,0.0004967495,0.0002921642,0.00060104,0.000230318,0.0008047838,0.004300462],"category_scores_gemma":[0.0004597702,0.0002873797,0.0004167886,0.0001206339,0.0002960759,0.0003843978,0.0006261237,0.001084628,0.0009861732],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000444816,"about_ca_system_score_gemma":0.0002783174,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002039782,"about_ca_topic_score_gemma":0.0002831284,"domain_scores_codex":[0.9995793,0.0001593315,0.00002745047,0.00003337154,0.00007235401,0.0001283241],"domain_scores_gemma":[0.9998373,0.00002749382,0.00004112718,0.00002155879,0.00002138394,0.00005120488],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005375402,0.0003187339,0.002037014,0.0002042308,0.00004866964,0.001227769,0.0001173946,0.0002449169,0.9773337,0.00129686,0.001374407,0.01042081],"study_design_scores_gemma":[0.0005901442,0.004306297,0.03431716,0.00008604573,0.0001287413,0.003885452,0.0005174349,0.005868542,0.9413765,0.002235843,0.006655786,0.00003198623],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9879863,0.003683208,0.004333225,0.000777875,0.0001871513,0.00005989536,0.0001795301,0.0001035641,0.00268934],"genre_scores_gemma":[0.9941165,0.0007612199,0.001179185,0.0002312448,0.00008951387,0.00005636068,0.000229777,0.000009988941,0.003326199],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004300462,"threshold_uncertainty_score":0.01438653,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008376785106394268,"score_gpt":0.2552494226828873,"score_spread":0.246872637576493,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}