{"id":"W1986393439","doi":"10.1083/jcb.201305159","title":"Pin1 promotes histone H1 dephosphorylation and stabilizes its binding to chromatin","year":2013,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"NOSM University; University of Alberta","funders":"National Institute of General Medical Sciences","keywords":"Histone H1; Biology; Histone H2A; Histone code; Chromatin; Phosphorylation; Histone methyltransferase; Cell biology; Histone-modifying enzymes; Dephosphorylation; Histone; Prolyl isomerase; Chromatin remodeling; PIN1; Molecular biology; Biochemistry; Nucleosome; DNA; Phosphatase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001065162,0.0003526555,0.0002279894,0.0001630738,0.0001790863,0.0003479318,0.0002247091,0.0002204684,0.001678547],"category_scores_gemma":[0.0001131305,0.0001948772,0.0002012032,0.0000850116,0.0002073801,0.0002101358,0.0003491209,0.00054696,0.0004114739],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003257618,"about_ca_system_score_gemma":0.0001131193,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002992409,"about_ca_topic_score_gemma":0.0005131588,"domain_scores_codex":[0.9998902,0.00001338871,0.000005396227,0.0000325955,0.00002501378,0.00003343614],"domain_scores_gemma":[0.9999365,0.00001174249,0.0000170105,0.000005740522,0.000004549519,0.00002450155],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009436852,0.00001189663,0.0001019622,0.0000385823,0.000003133435,0.00004066531,0.0000053984,0.00004949541,0.9986801,0.0001140902,0.0000286281,0.0008316857],"study_design_scores_gemma":[0.000007091393,0.0000724341,0.002769663,0.000003266382,0.000005346385,0.0001572403,0.00001202513,0.0006680936,0.9946004,0.00004961435,0.001651362,0.000003507241],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9885942,0.003609226,0.004559494,0.0001412757,0.00005022034,0.00002650027,0.0002914881,0.00009856953,0.002629114],"genre_scores_gemma":[0.9959966,0.0007397609,0.001213208,0.00004056633,0.000009951015,0.00001361765,0.0002712506,0.00001267697,0.001702206],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001678547,"threshold_uncertainty_score":0.005615354,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01059527843884173,"score_gpt":0.2555581846117834,"score_spread":0.2449629061729416,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}