{"id":"W1986522335","doi":"10.1021/bi0014498","title":"Biological Activities of Glucagon-Like Peptide-1 Analogues in Vitro and in Vivo","year":2001,"lang":"en","type":"article","venue":"Biochemistry","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":106,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Université du Québec à Montréal","funders":"","keywords":"In vivo; Receptor; Chemistry; In vitro; Secretin; Glucagon; Biological activity; Glucagon-like peptide-1; Endocrinology; Internal medicine; Glucagon-like peptide 1 receptor; Peptide; Glucose homeostasis; Biochemistry; Insulin; Biology; Diabetes mellitus; Hormone; Agonist; Medicine; Pancreas; Insulin resistance; Type 2 diabetes","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005842642,0.0000830412,0.0001862021,0.00005658559,0.000006185391,0.000003790738,0.00003144966,0.00006315712,0.00003625525],"category_scores_gemma":[0.0000191909,0.0000673093,0.00002771578,0.00009906836,0.0000723237,0.00002014578,0.00003892015,0.00004729693,9.201906e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005082509,"about_ca_system_score_gemma":0.00001280284,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000436419,"about_ca_topic_score_gemma":0.000008655477,"domain_scores_codex":[0.9995293,0.000006845662,0.0001204595,0.0001502726,0.00005927687,0.000133841],"domain_scores_gemma":[0.9997969,0.00002501785,0.00002883678,0.000107587,0.000006400022,0.000035276],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002418487,0.000271269,0.1786519,0.0000918462,0.00002780657,0.00006366692,0.00004777622,1.633705e-7,0.8181757,0.000006144346,0.0003614441,0.002060397],"study_design_scores_gemma":[0.001214677,0.00008180424,0.04502378,0.00008850222,0.00001942521,0.000005978156,0.0006226169,0.00002047081,0.9514718,0.00002923136,0.001339113,0.00008260799],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909832,0.0005991195,9.063916e-7,0.0001213945,0.00001620929,0.00008833036,0.000005576951,0.00001252645,0.008172772],"genre_scores_gemma":[0.9977459,0.0003835583,0.0001616713,0.00006641431,0.00002370674,0.00001364214,0.00002714684,0.0000040065,0.001574002],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1336281,"threshold_uncertainty_score":0.2744794,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01675697021728593,"score_gpt":0.2497599687336935,"score_spread":0.2330029985164076,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}