{"id":"W1986522335","doi":"10.1021/bi0014498","title":"Biological Activities of Glucagon-Like Peptide-1 Analogues in Vitro and in Vivo","year":2001,"lang":"en","type":"article","venue":"Biochemistry","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":106,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Université du Québec à Montréal","funders":"","keywords":"In vivo; Receptor; Chemistry; In vitro; Secretin; Glucagon; Biological activity; Glucagon-like peptide-1; Endocrinology; Internal medicine; Glucagon-like peptide 1 receptor; Peptide; Glucose homeostasis; Biochemistry; Insulin; Biology; Diabetes mellitus; Hormone; Agonist; Medicine; Pancreas; Insulin resistance; Type 2 diabetes","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002678544,0.0004342038,0.000315994,0.0001625074,0.0000726672,0.0002498904,0.0001460748,0.0002338518,0.001008255],"category_scores_gemma":[0.0001883228,0.0001045876,0.0002812849,0.0001267248,0.0001468004,0.0002059611,0.00007212416,0.0007015801,0.0002444066],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001812639,"about_ca_system_score_gemma":0.00009706975,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001902879,"about_ca_topic_score_gemma":0.0001827487,"domain_scores_codex":[0.999836,0.00005720204,0.00001509022,0.00002684803,0.00003567646,0.00002915805],"domain_scores_gemma":[0.9998491,0.00004877542,0.00003549648,0.00001741026,0.00001563447,0.00003361117],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004627022,0.00008744773,0.0001214845,0.00004852225,0.000009515732,0.0000321114,0.000007903601,0.0001342239,0.9970573,0.0000336853,0.00004079656,0.001964249],"study_design_scores_gemma":[0.00004115094,0.00404059,0.002308935,0.000004309836,0.00003152772,0.0002986797,0.00001570056,0.0003703595,0.9909923,0.00002653154,0.001863811,0.000006144129],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9869494,0.007923028,0.002523795,0.000091273,0.00006631709,0.00003397718,0.0004374474,0.00005696579,0.001917734],"genre_scores_gemma":[0.9891288,0.003846174,0.003840905,0.0001422537,0.00005393011,0.00005181079,0.001509677,0.00002525733,0.001401333],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001008255,"threshold_uncertainty_score":0.003372908,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01675697021728593,"score_gpt":0.2497599687336935,"score_spread":0.2330029985164076,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}