{"id":"W1986526249","doi":"10.1371/journal.pone.0035400","title":"Dissociation of Immune Responses from Pathogen Colonization Supports Pattern Recognition in C. elegans","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Buck Institute for Research on Aging; Natural Sciences and Engineering Research Council of Canada; Ellison Medical Foundation","keywords":"Biology; Immune system; Pathogen; Caenorhabditis elegans; Innate immune system; Pseudomonas aeruginosa; Pattern recognition receptor; Microbiology; Pathogen-associated molecular pattern; Colonization; Immunity; Immunology; Genetics; Gene; Bacteria","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001737418,0.0003598428,0.000274513,0.0004275593,0.0002335063,0.0003597169,0.0003029691,0.0003960066,0.0005924903],"category_scores_gemma":[0.0002972565,0.0002793241,0.0003315668,0.00009291342,0.0004329135,0.0003358121,0.000475985,0.0007296566,0.0001918975],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000459508,"about_ca_system_score_gemma":0.0003922307,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001645496,"about_ca_topic_score_gemma":0.003841014,"domain_scores_codex":[0.9997982,0.00001311322,0.00001986955,0.00005226329,0.00006639474,0.00005006483],"domain_scores_gemma":[0.9996284,0.00008068014,0.0000934889,0.00003864487,0.00004352284,0.0001151984],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008378626,0.00001175143,0.0003445708,0.00002185657,0.000002128451,0.00003750102,0.000009347669,0.0000301322,0.9988809,0.00005847757,0.00001389013,0.0005055655],"study_design_scores_gemma":[0.0000443153,0.0004457927,0.1098669,0.0000347848,0.00003147266,0.0004788856,0.00009772307,0.002822243,0.8846245,0.0002688009,0.001251176,0.00003346498],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980433,0.0003673467,0.0006629713,0.00005275865,0.00001035574,0.000008367861,0.0002123936,0.00003391874,0.0006087336],"genre_scores_gemma":[0.9965229,0.000336947,0.001552093,0.00008835701,0.000005615957,0.00003575094,0.0002973059,0.00002282058,0.001138349],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001645496,"threshold_uncertainty_score":0.003333986,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02635306433980713,"score_gpt":0.2219592484949565,"score_spread":0.1956061841551494,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}