{"id":"W1986532337","doi":"10.1016/j.yjmcc.2011.12.004","title":"Increased neointimal formation in cystathionine gamma-lyase deficient mice: Role of hydrogen sulfide in α5β1-integrin and matrix metalloproteinase-2 expression in smooth muscle cells","year":2011,"lang":"en","type":"article","venue":"Journal of Molecular and Cellular Cardiology","topic":"Sulfur Compounds in Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan; Lakehead University","funders":"Canadian Institutes of Health Research; National Institutes of Health; Heart and Stroke Foundation of Canada","keywords":"Integrin; Fibronectin; Cystathionine beta synthase; Matrix metalloproteinase; Cystathionine gamma-lyase; Chemistry; Vascular smooth muscle; Cell biology; Cell migration; Endogeny; Extracellular matrix; Molecular biology; Endocrinology; Biochemistry; Receptor; Biology; Enzyme; Cell; Smooth muscle; Cysteine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009446432,0.0001996776,0.0005396213,0.0003533061,0.0000186688,0.000006355873,0.0001804388,0.0002918873,0.000005535991],"category_scores_gemma":[0.0001067992,0.0001799831,0.0001447716,0.0001382591,0.0001357743,0.00001625351,0.0001589725,0.0002741441,5.268744e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003434406,"about_ca_system_score_gemma":0.00005938674,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001387249,"about_ca_topic_score_gemma":0.00005759976,"domain_scores_codex":[0.9980211,0.0005480015,0.0007420701,0.0002781267,0.0001253636,0.0002853711],"domain_scores_gemma":[0.9992464,0.00002844602,0.0003358472,0.0002144879,0.00008690853,0.00008795017],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005461908,0.00008918247,0.005994479,0.00003234224,0.00002806102,0.0004838397,0.0002465382,0.0003542316,0.9915705,0.000041007,0.000004002146,0.0006096772],"study_design_scores_gemma":[0.001953135,0.0006024349,0.006607971,0.00006049872,0.00003170885,0.000370778,0.0005605928,0.0001845744,0.9887292,0.0004072614,0.000320156,0.0001716455],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9869989,0.01025052,0.002272122,0.00001404171,0.00006105901,0.0002153021,0.000007127695,0.000002038838,0.0001789355],"genre_scores_gemma":[0.996866,0.0004790477,0.002539477,0.00003051868,0.00003114797,0.0000100275,0.00002329578,0.00001732429,0.000003114856],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009867189,"threshold_uncertainty_score":0.7339498,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007425128769871775,"score_gpt":0.2106404049409592,"score_spread":0.2032152761710874,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}