{"id":"W1986577071","doi":"10.1097/fjc.0b013e3182163b82","title":"Pharmacogenomics of Cardiovascular Drugs and Adverse Effects in Pediatrics","year":2011,"lang":"en","type":"review","venue":"Journal of Cardiovascular Pharmacology","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia; Child and Family Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Pharmacogenomics; Medicine; Adverse effect; Intensive care medicine; Pediatrics; Pharmacology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["metaepi_narrow","research_integrity"],"category_scores_codex":[0.008281632,0.001305382,0.008529241,0.002150643,0.0001345692,0.00001671631,0.001462596,0.001614216,0.000261546],"category_scores_gemma":[0.0001858098,0.001196624,0.008349807,0.001185332,0.0005938121,0.0002686434,0.0005956997,0.004149672,0.00004065692],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003107983,"about_ca_system_score_gemma":0.001205426,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003193253,"about_ca_topic_score_gemma":4.978725e-7,"domain_scores_codex":[0.9879907,0.005693237,0.003380216,0.0009064695,0.0008489241,0.001180405],"domain_scores_gemma":[0.9941975,0.001299957,0.002277169,0.0007102286,0.0006260973,0.0008890871],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003206262,0.0005993018,0.00003545332,0.01753751,0.04186354,0.001731828,0.000650866,0.0028585,0.0001117114,0.00006778124,0.001050716,0.9331722],"study_design_scores_gemma":[0.007368266,0.0001964213,0.000009759568,0.0006161087,0.08758693,0.001153832,0.0000371712,0.000061384,0.0008475456,0.00008456474,0.9011843,0.0008537832],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003820468,0.9835963,0.0002146182,0.00001043609,0.009444679,0.001880235,0.0001319861,0.00002715614,0.000874067],"genre_scores_gemma":[0.001935929,0.9942165,0.0004779252,0.0001956946,0.00278873,0.0001118656,0.00001758077,0.0002118545,0.00004393236],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9323184,"threshold_uncertainty_score":0.9999698,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08207730166137694,"score_gpt":0.3996353361034898,"score_spread":0.3175580344421129,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}