{"id":"W1986588900","doi":"10.1016/s0022-2836(02)00858-6","title":"Myxoma Virus Immunomodulatory Protein M156R is a Structural Mimic of Eukaryotic Translation Initiation Factor eIF2α","year":2002,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Bacteriophages and microbial interactions","field":"Environmental Science","cited_by":52,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ontario Institute for Cancer Research; University of Toronto","funders":"Pacific Northwest National Laboratory; Battelle; National Institute of General Medical Sciences; Biological and Environmental Research; National Institutes of Health; U.S. Department of Energy","keywords":"Eukaryotic initiation factor; eIF2; Biology; EIF4A1; Protein kinase R; Initiation factor; Eukaryotic translation; Internal ribosome entry site; Cell biology; Translation (biology); Protein kinase A; Phosphorylation; Biochemistry; Cyclin-dependent kinase 2; Messenger RNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00005935313,0.00009390768,0.0001654176,0.00006524234,0.00003757958,0.000008751044,0.0001296139,0.00009081579,0.003015955],"category_scores_gemma":[0.00001586752,0.0000793999,0.0001358035,0.00008439922,0.00008565354,0.0001680976,0.00002231759,0.0001563928,0.00003646487],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006808076,"about_ca_system_score_gemma":0.000007480088,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007582486,"about_ca_topic_score_gemma":0.00001334988,"domain_scores_codex":[0.9992285,0.00008998279,0.000377448,0.0001015707,0.00007880784,0.0001237271],"domain_scores_gemma":[0.9994619,0.00001276224,0.0003581436,0.0001019953,0.0000252462,0.00003992886],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002647869,0.00003352795,0.0008326148,0.000004316489,0.00003145539,0.000007703363,0.0003007556,0.00003735477,0.9914543,0.000008696846,0.00004401909,0.0072188],"study_design_scores_gemma":[0.0007010461,0.0006284497,0.1600124,0.00003408748,0.00004221086,0.0002288976,0.00002382691,0.0004714719,0.8360362,0.0003840195,0.001274823,0.0001625476],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974295,0.0003231147,0.001462321,0.000298487,0.0001650415,0.0001130287,0.00002011216,0.000003689062,0.0001846672],"genre_scores_gemma":[0.9984559,0.00002904973,0.001291728,0.0001470101,0.00002716237,0.000001159048,0.00000324262,0.00000828008,0.00003641983],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1591798,"threshold_uncertainty_score":0.9978954,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01614519017755071,"score_gpt":0.2514004717801517,"score_spread":0.235255281602601,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}