{"id":"W1986625994","doi":"10.1021/bi020059d","title":"The Many Tales of a Tail:  Carboxyl-Terminal Tail Heterogeneity Specializes Histone H2A Variants for Defined Chromatin Function","year":2002,"lang":"en","type":"review","venue":"Biochemistry","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"","keywords":"Chromatin; Histone; Epigenetics; Nucleosome; Histone code; Biology; Histone-modifying enzymes; Chromatin remodeling; Histone H2A; Genetics; Cell biology; Histone H1; DNA; Computational biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002503993,0.0005710418,0.0009160002,0.0000365367,0.0002216856,0.00005752438,0.000636411,0.0007401185,0.00002193913],"category_scores_gemma":[0.0001438018,0.0004622662,0.0007885713,0.000103196,0.0002401263,0.000002504376,0.0002313066,0.0001697883,0.00000737526],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001112058,"about_ca_system_score_gemma":0.0002949411,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009328303,"about_ca_topic_score_gemma":0.00001820924,"domain_scores_codex":[0.9977558,0.00006466552,0.0008659982,0.0006890224,0.0002009029,0.0004235872],"domain_scores_gemma":[0.9978114,0.00005675262,0.0008924974,0.0009922351,0.0001389913,0.0001081536],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002819018,0.0006013135,0.00002299444,0.0395309,0.002203649,0.00002156238,0.00003584826,0.000007167801,0.2447961,0.0002904662,0.01825043,0.6939576],"study_design_scores_gemma":[0.000569274,0.0002558188,0.00001319608,0.001107225,0.0008760476,0.0001489179,0.00002422657,0.0001334117,0.01726071,0.00004092465,0.9788508,0.000719408],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02381965,0.9735277,0.0003073095,0.00001354402,0.0004219759,0.0006746627,0.000749501,0.00001738844,0.0004683052],"genre_scores_gemma":[0.007296747,0.9861695,0.0007672035,0.00001677205,0.001000702,0.0002813459,0.001913031,0.0001144177,0.002440287],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9606004,"threshold_uncertainty_score":0.9997829,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02260757523677268,"score_gpt":0.2836793136398646,"score_spread":0.2610717384030919,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}