{"id":"W1986658649","doi":"10.1165/rcmb.2006-0040oc","title":"Induction of the Plasminogen Activator System by Mechanical Stimulation of Human Bronchial Epithelial Cells","year":2006,"lang":"en","type":"article","venue":"American Journal of Respiratory Cell and Molecular Biology","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Urokinase receptor; Plasminogen activator; Urokinase; Plasmin; Downregulation and upregulation; Molecular biology; Chemistry; Tissue plasminogen activator; Stimulation; Activator (genetics); Fibrinolysis; Plasminogen activator inhibitor-1; Immunostaining; Receptor; Biology; Endocrinology; Internal medicine; Gene; Immunology; Medicine; Immunohistochemistry; Biochemistry; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002352997,0.0001292519,0.0002789236,0.00005540747,0.00005111431,0.000003697078,0.0001688422,0.0001318655,0.000001922344],"category_scores_gemma":[0.00001383794,0.00009464286,0.0001501118,0.00008236643,0.0002456803,0.000004961743,0.0000670947,0.0001182143,1.689182e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001505688,"about_ca_system_score_gemma":0.00009122782,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006148661,"about_ca_topic_score_gemma":0.000002007968,"domain_scores_codex":[0.9988297,0.0002862093,0.0004540386,0.0001685604,0.0001232974,0.0001382593],"domain_scores_gemma":[0.9988118,0.00001053441,0.0008209515,0.0001793911,0.0001230839,0.00005427541],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001442921,0.00006403343,0.0002509252,0.00001774929,0.00003517942,0.000001356066,0.000007719106,0.0000262238,0.9981375,0.000356511,0.0001443657,0.0008141776],"study_design_scores_gemma":[0.0006384985,0.002588378,0.00008962389,0.00001721425,0.0000455928,0.00001447668,0.00006637421,0.000004807619,0.9944144,0.000117295,0.001909627,0.00009368792],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994994,0.0004660731,0.004136428,0.00001244665,0.000173518,0.0001197912,0.00003193259,0.000002062362,0.00006375821],"genre_scores_gemma":[0.9994181,0.00000955344,0.0002637892,0.00008517586,0.0001914816,0.000002320322,0.000007358477,0.00001331737,0.000008880055],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004424133,"threshold_uncertainty_score":0.3859424,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004991182944545979,"score_gpt":0.2243617721674453,"score_spread":0.2193705892228993,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}