{"id":"W1986658649","doi":"10.1165/rcmb.2006-0040oc","title":"Induction of the Plasminogen Activator System by Mechanical Stimulation of Human Bronchial Epithelial Cells","year":2006,"lang":"en","type":"article","venue":"American Journal of Respiratory Cell and Molecular Biology","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Urokinase receptor; Plasminogen activator; Urokinase; Plasmin; Downregulation and upregulation; Molecular biology; Chemistry; Tissue plasminogen activator; Stimulation; Activator (genetics); Fibrinolysis; Plasminogen activator inhibitor-1; Immunostaining; Receptor; Biology; Endocrinology; Internal medicine; Gene; Immunology; Medicine; Immunohistochemistry; Biochemistry; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002406768,0.0003058486,0.0003468319,0.0002741991,0.0001784208,0.0003289601,0.0001482566,0.0002027042,0.002594926],"category_scores_gemma":[0.0002474762,0.0001488166,0.0003235626,0.000311665,0.0001784575,0.00009371139,0.0002903061,0.0005129898,0.0006793967],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002987327,"about_ca_system_score_gemma":0.0002210376,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009083629,"about_ca_topic_score_gemma":0.001263488,"domain_scores_codex":[0.9995536,0.00008394181,0.00003238653,0.00005236543,0.0001762874,0.000101397],"domain_scores_gemma":[0.9998828,0.00003289906,0.00001795027,0.00001854875,0.00002183775,0.00002587696],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001638332,0.00004906805,0.0002021173,0.00004832796,0.000004748109,0.00004044087,0.00001849683,0.00004354682,0.9978564,0.00003557322,0.00008639087,0.001451042],"study_design_scores_gemma":[0.00005543814,0.001419374,0.015136,0.00001356962,0.0000188262,0.0003046569,0.00007233751,0.001239897,0.9771991,0.00004116887,0.004491001,0.000008644033],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887992,0.003836256,0.002617904,0.0002826347,0.0001205166,0.0001538285,0.001021526,0.00008133591,0.003086829],"genre_scores_gemma":[0.9883952,0.001585685,0.004360228,0.0001559163,0.00009005363,0.0002412646,0.002116687,0.000009746303,0.003045274],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002594926,"threshold_uncertainty_score":0.00868088,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004991182944545979,"score_gpt":0.2243617721674453,"score_spread":0.2193705892228993,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}