{"id":"W1986659221","doi":"10.1016/j.vaccine.2008.05.018","title":"CD40L expressed from the canarypox vector, ALVAC, can boost immunogenicity of HIV-1 canarypox vaccine in mice and enhance the in vitro expansion of viral specific CD8+ T cell memory responses from HIV-1-infected and HIV-1-uninfected individuals","year":2008,"lang":"en","type":"article","venue":"Vaccine","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":54,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; Sanofi Pasteur; Ontario HIV Treatment Network","keywords":"Virology; Immunogenicity; Cytotoxic T cell; Biology; CD40; CTL*; CD8; Immunology; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001980678,0.0004509685,0.0002140565,0.0004050703,0.0001931719,0.0004750403,0.0001557818,0.0004190956,0.001497017],"category_scores_gemma":[0.0001558972,0.000165597,0.0001843748,0.0001398453,0.0002756568,0.0003116309,0.0001895652,0.001158966,0.0004196731],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000436157,"about_ca_system_score_gemma":0.0002255817,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000552371,"about_ca_topic_score_gemma":0.0005676738,"domain_scores_codex":[0.9998609,0.00002157386,0.000006780352,0.00001839028,0.0000384978,0.00005385912],"domain_scores_gemma":[0.9999089,0.00002102485,0.00001985449,0.00001456029,0.000007808711,0.0000276752],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003019937,0.0002048404,0.000205531,0.0000437074,0.000008696718,0.00004913686,0.00002201992,0.0001267051,0.9960485,0.0003319385,0.0001766413,0.002480391],"study_design_scores_gemma":[0.0001654136,0.001237951,0.003769193,0.00002101626,0.00004691364,0.000327542,0.00003348485,0.002079605,0.9859173,0.0002783657,0.006116021,0.000007304976],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951663,0.001132532,0.0009701136,0.0001554507,0.00007557277,0.00002393985,0.0001334542,0.00007346815,0.002269218],"genre_scores_gemma":[0.9938743,0.0007223858,0.001098547,0.00006170404,0.00003713301,0.00001789648,0.0004786518,0.00002087067,0.003688577],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001497017,"threshold_uncertainty_score":0.005008042,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008697997792868792,"score_gpt":0.2092825887201882,"score_spread":0.2005845909273194,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}