{"id":"W1986747449","doi":"10.1007/s11538-009-9465-z","title":"Multistability in a Model for CTL Response to HTLV-I Infection and Its Implications to HAM/TSP Development and Prevention","year":2009,"lang":"en","type":"article","venue":"Bulletin of Mathematical Biology","topic":"T-cell and Retrovirus Studies","field":"Immunology and Microbiology","cited_by":63,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"National Institutes of Health; Natural Sciences and Engineering Research Council of Canada; Mitacs","keywords":"CTL*; Tropical spastic paraparesis; Cytotoxic T cell; Immunology; Virology; CD8; Asymptomatic carrier; Viral load; Virus; Biology; T cell; Asymptomatic; Immune system; Medicine; Myelopathy; Genetics; In vitro; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005095259,0.0005528809,0.001006612,0.0008979012,0.0008810389,0.001199763,0.0009087746,0.001370255,0.00333306],"category_scores_gemma":[0.001759996,0.0003503636,0.001054174,0.0003212258,0.001145971,0.000988782,0.001253237,0.001060758,0.000280688],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009654476,"about_ca_system_score_gemma":0.0007501549,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002609719,"about_ca_topic_score_gemma":0.001452981,"domain_scores_codex":[0.9998198,0.00006590298,0.000007828578,0.00002745147,0.00002901901,0.00005001633],"domain_scores_gemma":[0.9992199,0.0003582215,0.0001534467,0.00004477528,0.0001001685,0.0001235529],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0002218021,0.0001263514,0.002236719,0.0001207662,0.0001205149,0.000716353,0.0004168736,0.5990208,0.01901854,0.3715821,0.002310932,0.004108318],"study_design_scores_gemma":[0.00003918173,0.00005038207,0.0003657726,0.000009025025,0.00001938543,0.00007493774,0.00004111417,0.9483025,0.0003003046,0.05047744,0.0003045997,0.00001534345],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7604982,0.0006725959,0.2130921,0.003646576,0.0001832731,0.00006603781,0.0002058164,0.0003327829,0.02130263],"genre_scores_gemma":[0.9862611,0.0001565203,0.005410408,0.000150216,0.00004594524,0.0000671103,0.00004668186,0.00005791734,0.007804191],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00333306,"threshold_uncertainty_score":0.01115018,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0331019302674516,"score_gpt":0.3045446681316846,"score_spread":0.271442737864233,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}