{"id":"W1986750567","doi":"10.1074/jbc.m805989200","title":"Met Receptor Tyrosine Kinase Degradation Is Altered in Response to the Leucine-rich Repeat of the Listeria Invasion Protein Internalin B","year":2008,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Liver physiology and pathology","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Cancer Institute; Canadian Institutes of Health Research; National Institutes of Health; National Science Foundation","keywords":"Listeria; Tyrosine kinase; Tyrosine; Leucine-rich repeat; Leucine; Receptor tyrosine kinase; Listeria monocytogenes; Degradation (telecommunications); Receptor; Chemistry; Cancer research; Microbiology; Biology; Biochemistry; Bacteria; Amino acid; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007707,0.0001078068,0.0003218186,0.00003133924,0.0000463863,0.00000264261,0.0002526258,0.0001826581,0.0002211115],"category_scores_gemma":[0.001342197,0.00004778167,0.0001264676,0.0001858074,0.0001661699,0.00002797708,0.0001055327,0.0004224389,0.000005030064],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005724382,"about_ca_system_score_gemma":0.00008545823,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007706015,"about_ca_topic_score_gemma":7.866854e-7,"domain_scores_codex":[0.9987597,0.0003254919,0.0005092897,0.0001463872,0.0001341014,0.0001250656],"domain_scores_gemma":[0.9990246,0.0001527973,0.000356777,0.0002591851,0.0001420106,0.00006468342],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.007126426,0.0001384924,0.01937978,0.00002235356,0.00001904281,0.00005023643,0.0002772862,0.000002255416,0.9716005,0.000001371432,0.00119161,0.0001905985],"study_design_scores_gemma":[0.0008940542,0.0007979309,0.1315317,0.0002120303,0.00001496927,0.0005712405,0.00007280317,0.000002456636,0.8645823,0.00004410065,0.001224101,0.00005228434],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946158,0.0001882289,0.00001593229,0.00482278,0.0001117362,0.0001744871,0.00001042101,0.000003749227,0.00005689741],"genre_scores_gemma":[0.9976878,0.00005732608,0.000487198,0.0008025071,0.0002288194,0.000005766852,0.000005696284,0.000004563597,0.000720355],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.112152,"threshold_uncertainty_score":0.2421016,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05728358341463641,"score_gpt":0.2863063823079312,"score_spread":0.2290227988932948,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}