{"id":"W1986752474","doi":"10.1016/j.bbcan.2010.10.004","title":"The role of Stat5 transcription factors as tumor suppressors or oncogenes","year":2010,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Reviews on Cancer","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":124,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"STAT5; Carcinogenesis; Senescence; Biology; Transcription factor; Cancer research; DNA damage; Cell growth; Suppressor; Tumor suppressor gene; Cell biology; Context (archaeology); Cancer; Gene; Signal transduction; Genetics; DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003896771,0.0009619542,0.00321929,0.0002261031,0.0002386828,0.0000869518,0.0005987913,0.0003424675,0.0006098584],"category_scores_gemma":[0.000287022,0.0004833819,0.002149725,0.0005716204,0.0002546808,0.0001195457,0.0000640723,0.001330549,0.0001351506],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002282351,"about_ca_system_score_gemma":0.001148733,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002421706,"about_ca_topic_score_gemma":0.0001059078,"domain_scores_codex":[0.9960686,0.0004032873,0.001642223,0.0008127027,0.0005631951,0.0005099949],"domain_scores_gemma":[0.9961596,0.0005175288,0.001610132,0.001252918,0.0001988444,0.0002609355],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003432697,0.0005786032,3.752937e-7,0.01023335,0.0006436695,0.000005590944,0.0003032562,1.335863e-7,0.2547801,0.0001915929,0.004387587,0.7285324],"study_design_scores_gemma":[0.0002359677,0.0005925696,0.000006752142,0.02232271,0.00207324,0.00002418966,0.00004295853,0.000002044284,0.1352331,0.00001543449,0.8390298,0.0004212631],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0157666,0.9776716,7.436377e-7,0.0003937135,0.00115466,0.002968302,0.001141578,0.00006938689,0.0008333677],"genre_scores_gemma":[0.002318484,0.9943317,0.00004698486,0.0002805764,0.0007814317,0.0007971234,0.0003960936,0.000163566,0.0008840754],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8346422,"threshold_uncertainty_score":0.9997618,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07642542906217865,"score_gpt":0.3969584131348299,"score_spread":0.3205329840726512,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}