{"id":"W1986796288","doi":"10.1210/en.2011-1437","title":"Reduced Hippocampal Brain-Derived Neurotrophic Factor (BDNF) in Neonatal Rats after Prenatal Exposure to Propylthiouracil (PTU)","year":2012,"lang":"en","type":"article","venue":"Endocrinology","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Center for Research Resources; National Institute of Neurological Disorders and Stroke; National Institutes of Health","keywords":"Propylthiouracil; Endocrinology; Internal medicine; Brain-derived neurotrophic factor; Hippocampal formation; Neurotrophic factors; Offspring; Medicine; Central nervous system; Thyroid; Prenatal stress; Hormone; Neurotrophin; Pregnancy; Biology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000123961,0.0005340638,0.0004763333,0.000635833,0.0002198747,0.0002299709,0.0003175902,0.0004269124,0.001560756],"category_scores_gemma":[0.0002623086,0.0003361319,0.0002907784,0.0001941576,0.0006367948,0.0002870472,0.0003076272,0.001181889,0.0002483025],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006123608,"about_ca_system_score_gemma":0.0005393567,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005232,"about_ca_topic_score_gemma":0.009656658,"domain_scores_codex":[0.9997439,0.00001675111,0.00002567383,0.00008070562,0.00007517542,0.00005782696],"domain_scores_gemma":[0.9994864,0.00005097773,0.0001567567,0.00004183337,0.00006737679,0.0001965831],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009233298,0.00009036404,0.001187796,0.00005295304,0.0000125707,0.0001903271,0.00009310571,0.00002745978,0.9951941,0.00004062711,0.00004019087,0.002146995],"study_design_scores_gemma":[0.000052352,0.002520199,0.04595526,0.00001627214,0.00007701793,0.0005599374,0.0002846132,0.0004267769,0.9487935,0.00009705211,0.001196227,0.00002071169],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973422,0.0008833496,0.0007743319,0.00009662275,0.00004812668,0.00001352557,0.0003803727,0.00005893949,0.0004025397],"genre_scores_gemma":[0.9940627,0.0007624414,0.001368222,0.0000797162,0.0000101329,0.00007201477,0.000474525,0.00002812071,0.003142119],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005232,"threshold_uncertainty_score":0.0104031,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01813903673603831,"score_gpt":0.2734896538037987,"score_spread":0.2553506170677604,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}