{"id":"W1986900195","doi":"10.1107/s0907444912050330","title":"Structure of the cytoplasmic domain of TcpE, the inner membrane core protein required for assembly of the<i>Vibrio cholerae</i>toxin-coregulated pilus","year":2013,"lang":"en","type":"article","venue":"Acta Crystallographica Section D Biological Crystallography","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"Canadian Institutes of Health Research","keywords":"Pilin; Pilus; Vibrio cholerae; Inner membrane; Type VI secretion system; Bacterial outer membrane; Protein subunit; Translocon; Transmembrane protein; Integral membrane protein; Biology; Secretion; Transmembrane domain; Cell biology; Biophysics; Membrane protein; Chemistry; Biochemistry; Membrane; Escherichia coli; Virulence; Receptor; Bacteria; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001183878,0.0003695939,0.000285448,0.000202004,0.0003693315,0.0004648883,0.0005125912,0.0005619352,0.0009727936],"category_scores_gemma":[0.0003483338,0.0002086369,0.0002656841,0.00036542,0.0002774748,0.00030007,0.0001965815,0.0008783357,0.000510902],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001148948,"about_ca_system_score_gemma":0.0005862025,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007795024,"about_ca_topic_score_gemma":0.005092519,"domain_scores_codex":[0.9999223,0.000006494711,0.000003086766,0.00001739199,0.00003611155,0.00001459085],"domain_scores_gemma":[0.9998723,0.00002543409,0.00002897178,0.000005909496,0.00003477357,0.00003251531],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008024989,0.000207873,0.004915607,0.0004641917,0.00005904913,0.003064955,0.0002831351,0.005669341,0.9672092,0.001875169,0.005125534,0.01032358],"study_design_scores_gemma":[0.0005723451,0.0009633013,0.2948907,0.0003288397,0.0001940861,0.007388819,0.001197322,0.06737687,0.5155294,0.001750893,0.1095708,0.0002365956],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9770795,0.007081656,0.003723619,0.0005564406,0.0001399706,0.0000748507,0.003663792,0.0002068863,0.007473228],"genre_scores_gemma":[0.9791965,0.002022653,0.002688523,0.0002208375,0.00003295486,0.00003323474,0.01241485,0.00004642237,0.003344046],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007795024,"threshold_uncertainty_score":0.01549935,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01410335145057131,"score_gpt":0.2320522715471057,"score_spread":0.2179489200965344,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}