{"id":"W1987014914","doi":"10.1210/en.2002-220984","title":"Isolation of the Novel Human Guanine Nucleotide Exchange Factor Src Homology 3 Domain-Containing Guanine Nucleotide Exchange Factor (SGEF) and of C-Terminal SGEF, an N-Terminally Truncated Form of SGEF, the Expression of Which Is Regulated by Androgen in Prostate Cancer Cells","year":2003,"lang":"en","type":"article","venue":"Endocrinology","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Université Laval","keywords":"Biology; Pleckstrin homology domain; Guanine nucleotide exchange factor; Molecular biology; LNCaP; Homology (biology); Complementary DNA; Gene; Guanosine; Cell biology; Biochemistry; Genetics; Prostate cancer; Signal transduction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002026595,0.0002765657,0.0005044315,0.0001393926,0.00009579791,0.00000658839,0.0002798309,0.0001929013,0.0001717696],"category_scores_gemma":[0.00005819899,0.0002054561,0.00009631706,0.0002341636,0.0003336181,0.00002497381,0.0001696917,0.000170491,2.02071e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002937505,"about_ca_system_score_gemma":0.00009557744,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003597339,"about_ca_topic_score_gemma":0.0005244128,"domain_scores_codex":[0.9980132,0.0002291788,0.0007544337,0.0004250527,0.0001837699,0.0003943758],"domain_scores_gemma":[0.9983278,0.00003744679,0.0008282392,0.0004888481,0.0002567981,0.00006087229],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003018736,0.0001503098,0.01278833,0.0001606812,0.0000548259,0.000005284294,0.002073572,0.00002132794,0.9835669,0.0001003659,0.00003447833,0.0007420477],"study_design_scores_gemma":[0.00215575,0.000787712,0.021873,0.0001154446,0.00003581703,0.00004738988,0.0003519895,0.00009746297,0.973727,0.0001190792,0.0004997067,0.0001896777],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971699,0.001348287,0.0001913877,0.00009979134,0.00008294172,0.0006894711,0.0003528655,0.000007843531,0.00005750944],"genre_scores_gemma":[0.9989761,0.0002020644,0.0004632606,0.00005667239,0.00002788404,0.0000401269,0.00008484949,0.0000343872,0.0001146727],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009839937,"threshold_uncertainty_score":0.8378255,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01522560507311269,"score_gpt":0.2622682634793503,"score_spread":0.2470426584062376,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}