{"id":"W1987014914","doi":"10.1210/en.2002-220984","title":"Isolation of the Novel Human Guanine Nucleotide Exchange Factor Src Homology 3 Domain-Containing Guanine Nucleotide Exchange Factor (SGEF) and of C-Terminal SGEF, an N-Terminally Truncated Form of SGEF, the Expression of Which Is Regulated by Androgen in Prostate Cancer Cells","year":2003,"lang":"en","type":"article","venue":"Endocrinology","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Université Laval","keywords":"Biology; Pleckstrin homology domain; Guanine nucleotide exchange factor; Molecular biology; LNCaP; Homology (biology); Complementary DNA; Gene; Guanosine; Cell biology; Biochemistry; Genetics; Prostate cancer; Signal transduction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001192666,0.0002316804,0.0001837218,0.0001711024,0.0001592849,0.0001573341,0.0001501987,0.0002791407,0.0007528322],"category_scores_gemma":[0.0001754584,0.0001132866,0.0003156057,0.0001096163,0.0001220137,0.0001543128,0.0001803197,0.0003970346,0.0005931671],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001762386,"about_ca_system_score_gemma":0.0002745015,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004243345,"about_ca_topic_score_gemma":0.0007149091,"domain_scores_codex":[0.9999263,0.000006847189,0.000006271186,0.00001871829,0.00002388944,0.0000179242],"domain_scores_gemma":[0.9999007,0.00001602178,0.00001736824,0.00001395538,0.00001736124,0.00003449453],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009112352,0.00001661411,0.001040766,0.00003531502,0.000006332626,0.0002209476,0.00001560588,0.00006065032,0.9945055,0.0001715683,0.00009248871,0.003743031],"study_design_scores_gemma":[0.0001380746,0.0008224425,0.05322278,0.00002674808,0.0001028403,0.009927375,0.00008487293,0.004060288,0.8877118,0.0006247567,0.0432498,0.00002818064],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9866925,0.00298483,0.00804029,0.0002690136,0.00004569871,0.00006288321,0.000732325,0.00004732522,0.001125027],"genre_scores_gemma":[0.9723356,0.001593245,0.01324074,0.0001453037,0.0000637889,0.0000639915,0.007716836,0.00002187092,0.004818531],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007528322,"threshold_uncertainty_score":0.002518475,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01522560507311269,"score_gpt":0.2622682634793503,"score_spread":0.2470426584062376,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}