{"id":"W1987039060","doi":"10.1016/j.molimm.2011.05.016","title":"Novel method for differentiation between Trastuzumab and host adaptive response","year":2011,"lang":"en","type":"article","venue":"Molecular Immunology","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University Medical Centre; McMaster University","funders":"Canadian Breast Cancer Research Alliance","keywords":"Trastuzumab; Epitope; Monoclonal antibody; Epidermal growth factor receptor; Antibody; SKBR3; Atezolizumab; Cancer research; Mutant; Biology; Pertuzumab; Cancer; Immune system; Cancer cell; Breast cancer; Immunology; Immunotherapy; Biochemistry; Human breast; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005007216,0.0007390319,0.0004565961,0.0008710191,0.0003076938,0.0005531987,0.0005060011,0.0007759657,0.001939345],"category_scores_gemma":[0.000384928,0.000300504,0.0003741364,0.0003025407,0.0002969741,0.0005863659,0.000572995,0.001464605,0.0008730765],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004257679,"about_ca_system_score_gemma":0.0002966984,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002632315,"about_ca_topic_score_gemma":0.000593979,"domain_scores_codex":[0.9996648,0.0000768969,0.00002283737,0.00009917697,0.00008399944,0.00005220899],"domain_scores_gemma":[0.9997728,0.00006994037,0.00002983271,0.00003762881,0.00005800815,0.0000317188],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000104863,0.0000405611,0.0003644756,0.00009487986,0.00001479122,0.00004774404,0.00003564474,0.00005893287,0.9861581,0.0008773718,0.0002394106,0.01196323],"study_design_scores_gemma":[0.0000401563,0.000191059,0.001316238,0.00001686614,0.00005403348,0.0004607927,0.00003295261,0.004545454,0.9847962,0.0006857926,0.007842456,0.00001804378],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.352866,0.007756923,0.6225225,0.0008779835,0.0007571405,0.0004856587,0.0008696718,0.001629358,0.0122348],"genre_scores_gemma":[0.6315253,0.003547491,0.3419077,0.0006663867,0.0001955677,0.0007996834,0.001136308,0.0001966048,0.02002499],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.001939345,"threshold_uncertainty_score":0.006487787,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08670512800503326,"score_gpt":0.3691413584816509,"score_spread":0.2824362304766176,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}