{"id":"W1987077730","doi":"10.1111/j.1462-5822.2005.00509.x","title":"Autophagy is an immediate macrophage response to Legionella pneumophila","year":2005,"lang":"en","type":"article","venue":"Cellular Microbiology","topic":"Legionella and Acanthamoeba research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":277,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; College of Medicine, University of Florida; National Institute of Allergy and Infectious Diseases; Tufts University School of Medicine; National Institutes of Health","keywords":"Autophagy; Vacuole; Phagosome; Legionella pneumophila; ATG8; Biology; Legionella; Microbiology; Cell biology; Macrophage; Endoplasmic reticulum; Phagocytosis; Secretion; Lysosome; Apoptosis; Biochemistry; Enzyme; In vitro; Bacteria; Cytoplasm","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005502775,0.0002953731,0.0002629959,0.0001546488,0.0001682786,0.00003874396,0.000593422,0.0004104915,0.0001452786],"category_scores_gemma":[0.0000620941,0.0002825112,0.0001460795,0.0001785268,0.0002035363,0.000007855096,0.0003338023,0.0002241751,0.001121056],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004638126,"about_ca_system_score_gemma":0.0001521537,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002030138,"about_ca_topic_score_gemma":0.00001893645,"domain_scores_codex":[0.9976784,0.0003357941,0.000320058,0.0008328818,0.00008305153,0.000749824],"domain_scores_gemma":[0.998633,0.00002386251,0.00006805389,0.0008043385,0.0001161911,0.0003545668],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007736264,0.0001158691,0.0001004987,0.000007273855,0.00003431526,0.00005362034,0.0002216338,0.00004010076,0.985107,0.00002100054,0.01185974,0.001665305],"study_design_scores_gemma":[0.0004814141,0.0004115419,0.0001441596,0.000003294187,0.000006319041,0.00008969094,0.00003165117,0.0000286698,0.6234988,0.00001026146,0.3750683,0.0002258933],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940764,0.00123259,0.0004519256,0.003165735,0.0002785896,0.000311011,0.00008495685,0.00003490175,0.0003639247],"genre_scores_gemma":[0.9847749,0.0001223506,0.0006951923,0.003998688,0.0008862867,0.00002709653,0.0003617282,0.00005844093,0.009075306],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3632086,"threshold_uncertainty_score":0.9999627,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01214002215081722,"score_gpt":0.2602465468689429,"score_spread":0.2481065247181257,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}