{"id":"W1987122320","doi":"10.1158/0008-5472.sabcs-4118","title":"Primary analysis of study MO19391, an open-label safety study of bevacizumab (B) plus taxane-based therapy as 1st-line treatment of patients (pts) with locally recurrent (LR) or metastatic breast cancer (mBC).","year":2009,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Treatment and Pharmacology","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre","funders":"","keywords":"Medicine; Taxane; Bevacizumab; Internal medicine; Population; Regimen; Clinical endpoint; Metastatic breast cancer; Phases of clinical research; Gastroenterology; Surgery; Oncology; Chemotherapy; Cancer; Breast cancer; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00695669,0.001980678,0.002800614,0.0006533026,0.0005813974,0.001442241,0.001070969,0.001725931,0.009142024],"category_scores_gemma":[0.004765673,0.0006968121,0.003103517,0.0008615273,0.0008532116,0.001047565,0.0006943154,0.002421264,0.001704151],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001331807,"about_ca_system_score_gemma":0.002756318,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008535055,"about_ca_topic_score_gemma":0.002302312,"domain_scores_codex":[0.9968994,0.001972593,0.0001866927,0.0004502484,0.0002892394,0.0002018666],"domain_scores_gemma":[0.9952061,0.001176846,0.001659219,0.0004375704,0.0004393337,0.001080944],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.9285365,0.01224447,0.01239088,0.002082039,0.006866823,0.000250516,0.000122171,0.0006999492,0.01128652,0.0001469202,0.004303444,0.02106975],"study_design_scores_gemma":[0.6510085,0.2506452,0.07709511,0.0001980638,0.006536207,0.0004027963,0.00005978514,0.001134541,0.003886582,0.0003144826,0.008652116,0.00006653822],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9476756,0.006156018,0.002352041,0.000762268,0.0002675363,0.01869887,0.01725555,0.0002409645,0.006591054],"genre_scores_gemma":[0.9654329,0.001983251,0.00267708,0.001621446,0.0005176919,0.01145342,0.01192054,0.0001018312,0.004291921],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009142024,"threshold_uncertainty_score":0.03679097,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1958622123719409,"score_gpt":0.5105737341160985,"score_spread":0.3147115217441576,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}