{"id":"W1987130154","doi":"10.1038/leu.2009.100","title":"Interleukin-21 effectively induces apoptosis in mantle cell lymphoma through a STAT1-dependent mechanism","year":2009,"lang":"en","type":"article","venue":"Leukemia","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Alberta Cancer Foundation","keywords":"Apoptosis; Cancer research; Biology; Mantle cell lymphoma; Tumor necrosis factor alpha; STAT1; Signal transduction; Lymphoma; Molecular biology; Cell biology; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001919028,0.0002547233,0.0002815376,0.000396288,0.0002245643,0.0002828832,0.0001613092,0.0002267087,0.001440485],"category_scores_gemma":[0.0001961576,0.0001188365,0.0003456048,0.0002638726,0.0002313575,0.0002050702,0.0002311769,0.0007749153,0.0002665188],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002650314,"about_ca_system_score_gemma":0.0003100262,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003105886,"about_ca_topic_score_gemma":0.0007979741,"domain_scores_codex":[0.9997745,0.00006641551,0.00002029147,0.00001371051,0.00005825362,0.00006688122],"domain_scores_gemma":[0.9998925,0.00003601937,0.00001756733,0.00001950444,0.00001388623,0.00002060865],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002226704,0.0005577115,0.001460767,0.0001866319,0.00005876005,0.0002883722,0.00006158435,0.0004544597,0.9710799,0.0004512042,0.0006961229,0.02247774],"study_design_scores_gemma":[0.0005507158,0.003570885,0.01077755,0.00001876665,0.000103362,0.0008285285,0.0000671209,0.001380392,0.9749005,0.0003041204,0.007486306,0.00001176922],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9874918,0.005118339,0.001479138,0.0003171246,0.000147536,0.00007068142,0.0002692521,0.0001078269,0.004998347],"genre_scores_gemma":[0.9970987,0.001075598,0.0004474107,0.0000711106,0.00002849291,0.00003082975,0.0002739422,0.000005762368,0.0009681446],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001440485,"threshold_uncertainty_score":0.004818916,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01327014297712055,"score_gpt":0.258905328367161,"score_spread":0.2456351853900405,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}