{"id":"W1987130154","doi":"10.1038/leu.2009.100","title":"Interleukin-21 effectively induces apoptosis in mantle cell lymphoma through a STAT1-dependent mechanism","year":2009,"lang":"en","type":"article","venue":"Leukemia","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Alberta Cancer Foundation","keywords":"Apoptosis; Cancer research; Biology; Mantle cell lymphoma; Tumor necrosis factor alpha; STAT1; Signal transduction; Lymphoma; Molecular biology; Cell biology; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000140491,0.0003205937,0.0005001719,0.0001500577,0.00006486879,0.00004397861,0.0001394071,0.0001858785,0.0001097994],"category_scores_gemma":[0.00002864852,0.000260291,0.0001533063,0.0002537604,0.00002822085,0.0001626411,0.00005407517,0.0001365929,0.0002508938],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003546697,"about_ca_system_score_gemma":0.0004283708,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001108833,"about_ca_topic_score_gemma":0.00006107127,"domain_scores_codex":[0.9982337,0.00007262866,0.0003446777,0.0005199744,0.0003607163,0.0004682714],"domain_scores_gemma":[0.9992318,0.0001024806,0.0001070282,0.000373815,0.00004473489,0.0001401041],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00423801,0.02239801,0.04341841,0.0009192422,0.001192624,0.00702489,0.03152606,0.0001057815,0.3570916,0.02736741,0.01151883,0.4931991],"study_design_scores_gemma":[0.01510015,0.001815533,0.1193992,0.0003479788,0.0001700787,0.00009847373,0.0004742933,0.00007178526,0.8563942,0.004628371,0.001128113,0.0003718041],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9823334,0.0003776542,0.00008782985,0.0004845151,0.0002035794,0.0006590935,0.00001225435,0.00009951266,0.01574216],"genre_scores_gemma":[0.9963593,0.0001792731,0.0008897371,0.001552876,0.00009973639,0.0001160859,0.0000287826,0.00002914021,0.0007449926],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4993027,"threshold_uncertainty_score":0.9999849,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01327014297712055,"score_gpt":0.258905328367161,"score_spread":0.2456351853900405,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}