{"id":"W1987137882","doi":"10.1016/j.jim.2015.02.008","title":"Analysis of CCR7 mediated T cell transfectant migration using a microfluidic gradient generator","year":2015,"lang":"en","type":"article","venue":"Journal of Immunological Methods","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Cell biology; Cell migration; Chemotaxis; Jurkat cells; C-C chemokine receptor type 7; Transfection; Biology; Chemokine receptor; Cell; Immunological synapse; CCL19; T cell; Chemokine; Cell culture; Immune system; Immunology; Receptor; T-cell receptor; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002701327,0.0003110025,0.001392509,0.0008743611,0.000109236,0.00001620212,0.0005122258,0.0006312372,0.0002976437],"category_scores_gemma":[0.000636902,0.0002139983,0.0007321418,0.001239929,0.0004602222,0.0001331071,0.00008567127,0.0007445876,0.00002057119],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001471463,"about_ca_system_score_gemma":0.0002233502,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000108035,"about_ca_topic_score_gemma":0.000005011264,"domain_scores_codex":[0.9948314,0.002823087,0.001494429,0.0002849864,0.0001094637,0.0004566189],"domain_scores_gemma":[0.997256,0.0006893494,0.001023513,0.0003328366,0.0006245535,0.00007375716],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007562945,0.0006705225,0.00144235,0.00001005303,0.002759759,0.00002751727,0.000727251,0.00008064113,0.9890275,0.00005087773,0.0001754594,0.00427175],"study_design_scores_gemma":[0.002575723,0.00186753,0.001245299,0.00002396631,0.002187279,0.0002152796,0.0007225051,0.0001161077,0.980609,0.0001224861,0.01007361,0.000241214],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.890715,0.07590809,0.03176248,0.0001441358,0.001214878,0.0001309842,0.00002100749,0.00002280746,0.00008063682],"genre_scores_gemma":[0.967164,0.002628442,0.02990683,0.00009051274,0.00004041172,0.000003776368,0.00003462902,0.00001886593,0.0001125723],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07644898,"threshold_uncertainty_score":0.8726599,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05792573210049035,"score_gpt":0.3235450517690553,"score_spread":0.265619319668565,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}