{"id":"W1987137882","doi":"10.1016/j.jim.2015.02.008","title":"Analysis of CCR7 mediated T cell transfectant migration using a microfluidic gradient generator","year":2015,"lang":"en","type":"article","venue":"Journal of Immunological Methods","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Cell biology; Cell migration; Chemotaxis; Jurkat cells; C-C chemokine receptor type 7; Transfection; Biology; Chemokine receptor; Cell; Immunological synapse; CCL19; T cell; Chemokine; Cell culture; Immune system; Immunology; Receptor; T-cell receptor; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002839129,0.0004321235,0.000292929,0.0003668088,0.00024262,0.0003619598,0.000343138,0.0003116012,0.00109259],"category_scores_gemma":[0.0001339645,0.0001367639,0.0002576136,0.0002792013,0.0001543025,0.000197727,0.0001442581,0.0006064279,0.000441234],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002907612,"about_ca_system_score_gemma":0.0002800852,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006814721,"about_ca_topic_score_gemma":0.0008295631,"domain_scores_codex":[0.9997442,0.00002569108,0.00002510054,0.00005857731,0.00007456653,0.00007179342],"domain_scores_gemma":[0.9998559,0.00004695615,0.0000239395,0.00001359592,0.00003596512,0.00002359577],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000427071,0.00002423756,0.0001273871,0.00001744037,0.000002871421,0.0000219849,0.00002191039,0.00003102143,0.9978932,0.0001229202,0.00007434333,0.001620021],"study_design_scores_gemma":[0.000007927701,0.00006999799,0.001807234,0.000002640067,0.000008930167,0.0000376532,0.00001566486,0.002734659,0.9945753,0.00003568236,0.0006985015,0.000005880287],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9390348,0.0008015769,0.05540714,0.0002418,0.000156235,0.0001727363,0.0009820629,0.0007069778,0.002496783],"genre_scores_gemma":[0.9112835,0.001131134,0.08048853,0.0001699354,0.00003352417,0.0004157318,0.001290104,0.000142637,0.005044778],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00109259,"threshold_uncertainty_score":0.003655076,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05792573210049035,"score_gpt":0.3235450517690553,"score_spread":0.265619319668565,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}